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Phase

Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 1Gynecologic 1Genitourinary 1Gastrointestinal 1

Conditions

Uterine Cervical Neoplasms 3Vulvar Neoplasms 1Vaginal Neoplasms 1Penile Neoplasms 1Oropharyngeal Neoplasms 1Head and Neck Neoplasms 1Colonic Neoplasms 1Camurati-Engelmann Syndrome 1Anus Neoplasms 1

Interventions

fludarabine 4aldesleukin 4Cyclophosphamide 4pembrolizumab 2fludarabine phosphate 2Polymerase Chain Reaction 2Gene Expression Profiling 2Counseling 2Bupropion 2Biopsy 2Adoptive Transfer 2entinostat 1bintrafusp alfa protein, human 1Zinc Oxide 1Vorinostat 1Varenicline 1Tomography, X-Ray Computed 1Tobacco Use Cessation Devices 1Taxes 1Surveys and Questionnaires 1Ritonavir 1Radiotherapy 1Psychiatric Rehabilitation 1Nicotine Replacement Therapy 1Nicotine 1NHS-IL12 immunocytokine 1Magnetic Resonance Imaging 1Liquid Biopsy 1Interleukin-2 1Indinavir 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × bintrafusp alfa protein, human × Gynecologic × Clear all
NCT04708470 2026-04-06

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
55 enrolled
GastrointestinalGenitourinaryGynecologicHead & Neck

Anus Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Oropharyngeal Neoplasms, Penile Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

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