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Phase

Phase 2 1Phase 1/2 1

Status

Withdrawn 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gynecologic 2Sarcoma 1

Conditions

Ovarian Neoplasms 109Uterine Cervical Neoplasms 57Endometrial Neoplasms 38Fallopian Tube Neoplasms 34Carcinoma, Ovarian Epithelial 27Breast Neoplasms 25Neoplasms 15Carcinoma, Non-Small-Cell Lung 13Pancreatic Neoplasms 12Uterine Cervical Dysplasia 11Recurrence 11Stomach Neoplasms 10Neoplasm Metastasis 10Lung Neoplasms 9Colorectal Neoplasms 9Uterine Neoplasms 8Triple Negative Breast Neoplasms 8Sarcoma 8Urinary Bladder Neoplasms 7Melanoma 6Esophageal Neoplasms 6Vulvar Neoplasms 5Vaginal Neoplasms 5Testicular Neoplasms 5Lymphoma, Non-Hodgkin 5Small Cell Lung Carcinoma 4Sezary Syndrome 4Rectal Neoplasms 4Prostatic Neoplasms 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 4

Interventions

Taxes 2Paclitaxel 2Magnetic Resonance Spectroscopy 2olaparib 1liposomal doxorubicin 1copanlisib 1Topotecan 1Specimen Handling 1Immunoglobulin G 1Doxorubicin 1Disulfides 1Bevacizumab 1ASTX-660 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Withdrawn × Platinum-Refractory Fallopian Tube Carcinoma × Gynecologic × Clear all
NCT06393751 2025-06-03

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

National Cancer Institute (NCI)

Phase 1/2 Withdrawn
GynecologicSarcoma

Platinum-Refractory Fallopian Tube Carcinoma

NCT05295589 2023-09-26

Comparing Standard of Care Chemotherapy Treatment to the Combination of Copanlisib and Olaparib for Recurrent Platinum Resistant Ovarian Cancer That Has Progressed Through PARP Inhibitor Therapy

National Cancer Institute (NCI)

Phase 2 Withdrawn
Gynecologic

Platinum-Refractory Fallopian Tube Carcinoma

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