Announcements Trials
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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Head & Neck 1Gynecologic 1Endocrine 1Breast 1

Conditions

Ovarian Neoplasms 15Uterine Cervical Neoplasms 12Carcinoma, Non-Small-Cell Lung 10Melanoma 9Triple Negative Breast Neoplasms 7Endometrial Neoplasms 7Stomach Neoplasms 6Carcinoma, Transitional Cell 6Carcinoma, Renal Cell 6Squamous Cell Carcinoma of Head and Neck 5Small Cell Lung Carcinoma 5Fallopian Tube Neoplasms 5Colorectal Neoplasms 4Carcinoma, Merkel Cell 4Carcinoma, Hepatocellular 4Neoplasm Metastasis 3Mesothelioma 3Esophageal Neoplasms 3Cholangiocarcinoma 3Vulvar Neoplasms 2Urinary Bladder Neoplasms 2Seminoma 2Sarcoma 2Prostatic Neoplasms 2Pancreatic Neoplasms 2Neoplasms 2Nasopharyngeal Carcinoma 2Lung Neoplasms 2Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2Leukemia, Myeloid, Acute 2

Interventions

aldesleukin 2Trastuzumab 2zimberelimab 1trametinib 1tipifarnib 1sargramostim 1fludarabine 1dabrafenib 1cobimetinib 1Vemurafenib 1Nivolumab 1Ipilimumab 1Interleukin-12 Subunit p35 1Interleukin-12 1Cyclophosphamide 1CTLA-4 Antigen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Thyroid Carcinoma, Anaplastic × Ipilimumab × Gynecologic × Clear all
NCT03449108 2026-05-22

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
30 enrolled
BreastEndocrineGynecologicHead & NeckSarcoma

Bone Neoplasms, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Giant Cell Tumor of Bone, Histiocytoma, Malignant Fibrous, Triple Negative Breast Neoplasms, Thyroid Carcinoma, Anaplastic

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