Announcements Trials
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Phase

Phase 1/2 2

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 4Gynecologic 2Thoracic 1Sarcoma 1Other solid neoplasm 1NET 1Endocrine 1Dermatologic 1

Conditions

Ovarian Neoplasms 142Endometrial Neoplasms 85Uterine Cervical Neoplasms 71Breast Neoplasms 42Fallopian Tube Neoplasms 38Colorectal Neoplasms 34Carcinoma, Non-Small-Cell Lung 32Pancreatic Neoplasms 24Neoplasms 23Prostatic Neoplasms 22Neoplasm Metastasis 21Stomach Neoplasms 19Triple Negative Breast Neoplasms 18Urinary Bladder Neoplasms 17Esophageal Neoplasms 17Melanoma 16Squamous Cell Carcinoma of Head and Neck 15Lung Neoplasms 15Carcinoma, Renal Cell 15Carcinoma, Ovarian Epithelial 15Head and Neck Neoplasms 14Sarcoma 13Carcinoma, Hepatocellular 13Uterine Neoplasms 11Colonic Neoplasms 11Cholangiocarcinoma 11Carcinoma, Transitional Cell 11Rectal Neoplasms 10Vulvar Neoplasms 9Small Cell Lung Carcinoma 9

Interventions

pembrolizumab 1denileukin diftitox 1E7777 fusion protein 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Turcot syndrome × Gynecologic × 30 days × Clear all
NCT07213609 2026-06-05

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

GlaxoSmithKline

Phase 1/2 Recruiting
47 enrolled
GastrointestinalGynecologic

Turcot syndrome, Colonic Neoplasms, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05200559 2026-05-29

T-regulatory Cell Depletion With E7777 Combined With Pembrolizumab in Recurrent or Metastatic Solid Tumors

University of Pittsburgh

Phase 1/2 Active not recruiting
25 enrolled
Gynecologic

Turcot syndrome, Carcinoma, Ovarian Epithelial

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