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Phase

Phase 1/2 5Phase 2 3Phase EARLY_PHASE1 2Phase 1 2Phase NA 1

Status

Terminated 1Completed 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 7Genitourinary 4Dermatologic 4Thoracic 3Head & Neck 3CNS 3Other solid neoplasm 2Lymphoid 2Gynecologic 2Other hematologic neoplasm 1Breast 1

Conditions

Ovarian Neoplasms 675Breast Neoplasms 265Uterine Cervical Neoplasms 240Carcinoma, Non-Small-Cell Lung 218Endometrial Neoplasms 201Fallopian Tube Neoplasms 187Carcinoma, Ovarian Epithelial 175Colorectal Neoplasms 164Stomach Neoplasms 152Pancreatic Neoplasms 144Neoplasms 143Melanoma 118Lung Neoplasms 112Carcinoma, Renal Cell 111Triple Negative Breast Neoplasms 108Prostatic Neoplasms 108Squamous Cell Carcinoma of Head and Neck 98Neoplasm Metastasis 96Esophageal Neoplasms 90Urinary Bladder Neoplasms 85Head and Neck Neoplasms 83Sarcoma 69Small Cell Lung Carcinoma 64Carcinoma, Hepatocellular 64Colonic Neoplasms 56Carcinoma, Transitional Cell 49Kidney Neoplasms 41Testicular Neoplasms 38Peritoneal Neoplasms 37Anus Neoplasms 34

Interventions

Nivolumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Turcot syndrome × Gynecologic × Clear all
NCT06034860 2024-11-01

Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types

Molecular Templates, Inc.

Phase 1 Terminated
15 enrolled
DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Turcot syndrome, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma

NCT03652077 2021-11-15

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Incyte Corporation

Phase 1 Completed
40 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Turcot syndrome, Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

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