Clinical Trials

GastrointestinalGynecologicHead & Neck

257 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Uterine Cervical Neoplasms

NCT05489211 2026-03-19

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

454 enrolled

Phase 1 Active not recruiting

Biliary Tract Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06607185 2026-03-13

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

750 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT05413811 2026-02-17

ACT2

Phase NA Completed

180 enrolled

Phase 2 Active not recruiting

Acquired Immunodeficiency Syndrome, Uterine Cervical Neoplasms

NCT04762953 2026-02-03

STOPGAP

40 enrolled

Peritoneal Neoplasms, Stomach Neoplasms

NCT04329494 2025-12-10

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Phase 1 Recruiting

49 enrolled

Appendiceal Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT00766142 2025-08-29

COCHISE

Phase 2 Terminated

18 enrolled 9 charts

Colonic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05007106 2025-08-14

KEYVIBE-005

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

613 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT03314935 2025-08-12

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

Phase 1/2 Completed

149 enrolled 35 charts

Phase 1 Active not recruiting

Biliary Tract Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT03872947 2025-08-03

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

138 enrolled

DermatologicGastrointestinalGenitourinaryGynecologic

Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT02059499 2025-07-23

Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

91 enrolled 26 charts

BreastDermatologicGenitourinaryGynecologicThoracic

Squamous Intraepithelial Lesions, HIV Infections

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT03196180 2025-04-08

Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia

Phase EARLY_PHASE1 Completed

13 enrolled 10 charts

Uterine Cervical Dysplasia

NCT03197584 2025-02-21

QUILT-3.051: NANT Ovarian Cancer Vaccine: Combination Immunotherapy in Subjects With Epithelial Ovarian Cancer Who Have Progressed on or After Standard-of-care (SoC) Therapy

Phase 1/2 Withdrawn

Ovarian Neoplasms

NCT02135419 2024-07-26

ANCHOR

4,446 enrolled 13 charts

Squamous Intraepithelial Lesions, Acquired Immunodeficiency Syndrome, Anus Neoplasms, HIV Infections, Papillomavirus Infections

NCT04840264 2024-03-18

Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel Obstruction

79 enrolled

Peritoneal Neoplasms

NCT05733000 2023-03-10

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

GastrointestinalGenitourinaryGynecologicThoracic

94 enrolled

Adenocarcinoma of Lung, Carcinoma, Transitional Cell, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT00000758 2021-11-04

A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women

158 enrolled

Acquired Immunodeficiency Syndrome, AIDS-Related Complex, Uterine Cervical Diseases, Uterine Cervical Dysplasia, HIV Infections

NCT04595929 2020-11-25

GASPACCO

Phase NA Recruiting

304 enrolled

BreastGastrointestinalGynecologicHead & NeckThoracic

Peritoneal Neoplasms, Stomach Neoplasms

NCT02658214 2020-08-20

Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors

Phase 1 Completed

32 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Carcinoma, Pancreatic Ductal, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT01504256 2018-01-23

CatuNeo

42 enrolled

Adenocarcinoma, Peritoneal Neoplasms

NCT00352755 2016-12-13

A Phase II Study of Surgical Debulking With Peritonectomy and Biweekly Intraperitoneal 5FU With Systemic Oxaliplatin/5FU/Leucovorin in Patients With Pseudomyxoma Peritonei or Peritoneal Carcinomatosis

Phase 2 Terminated

18 enrolled 8 charts

Peritoneal Neoplasms

NCT00769405 2016-08-30

Systemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer

264 enrolled

Colonic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00004547 2015-11-18

Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and Chemotherapy

GastrointestinalGynecologicOther solid neoplasmThoracic

188 enrolled 11 charts

Abdominal Neoplasms, Colonic Neoplasms, Mesothelioma, Peritoneal Neoplasms

NCT00413322 2015-07-08

Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors

Phase 1 Completed

35 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinosarcoma, Chondrosarcoma, Solitary Pulmonary Nodule, Phyllodes Tumor, Esophageal Neoplasms, Facial Neoplasms, Fibrosarcoma, Head and Neck Neoplasms, Hemangiosarcoma, Kidney Neoplasms, Leiomyosarcoma, Liposarcoma, Lung Neoplasms, Lymphangiosarcoma, Mesothelioma, Mouth Neoplasms, Myosarcoma, Myxosarcoma, Neoplasms, Otorhinolaryngologic Neoplasms, Ovarian Neoplasms, Pancoast Syndrome, Parathyroid Neoplasms, Sarcoma, Osteosarcoma, Thyroid Neoplasms, Tracheal Neoplasms, Colorectal Neoplasms, Adenosarcoma, Mixed Tumor, Mesodermal, Mesothelioma, Cystic, Carcinoma, Small Cell, Pulmonary Sclerosing Hemangioma, Histiocytoma, Malignant Fibrous

NCT00004206 2014-06-24

Oxaliplatin and Fluorouracil in Treating Patients With Recurrent Ovarian Cancer

Phase 2 Unknown

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT01379482 2014-05-06

Neo-adjuvant Chemo + Peritonectomy + Hyperthermic Intraperitoneal Chemo in Peritoneal Carcinomatosis From Gastric Cancer

18 enrolled

Peritoneal Neoplasms, Stomach Neoplasms

NCT00023660 2013-11-19

Radiation Therapy Plus Celecoxib, Fluorouracil, and Cisplatin in Patients With Locally Advanced Cervical Cancer

Phase 1/2 Completed

84 enrolled

Uterine Cervical Neoplasms

NCT00003078 2013-07-09

Radiation Therapy With or Without Cisplatin or Fluorouracil in Treating Patients With Cancer of the Cervix

870 enrolled

Uterine Cervical Neoplasms

NCT00003209 2012-07-11

Radiation Therapy With or Without Chemotherapy After Surgery in Treating Patients With Stage IB or Stage IIA Cervical Cancer

700 enrolled

Uterine Cervical Neoplasms

NCT00782041 2009-09-15

Patients Who Have Failed First Line Treatment for Locally Advanced and/or Metastatic Cervical Cancer

Phase 2 Terminated

11 enrolled

Uterine Neoplasms

NCT00003135 2009-04-30

Whole Body Hyperthermia Combined With Chemotherapy in Treating Patients With Metastatic Breast, Ovarian, Endometrial, or Cervical Cancer

Phase 2 Unknown

34 enrolled

BreastGynecologic

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Breast Neoplasms, Male

NCT00001569 2008-03-04

Phase I Trial of Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin Plus Early Postoperative Intraperitoneal Paclitaxel and 5-FU for Peritoneal Carcinomatosis

Phase 1 Completed

74 enrolled

Adenocarcinoma, Carcinoma, Peritoneal Neoplasms

NCT00612495 2008-02-11

Endometrial Cancer - LOHP Alone and With 5FU

31 enrolled