Clinical Trials Browser

Breast Neoplasms, Colonic Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms

NCT02312661 2024-05-06

OVMET

Phase 1 Completed

15 enrolled

Gynecologic

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT04792749 2023-04-13

Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer

Phase 3 Unknown

77 enrolled

Gynecologic

Endometrial Neoplasms

NCT02201381 2022-07-18

METRICS

Phase 3 Withdrawn

BreastCNSGastrointestinalGynecologic

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Triple Negative Breast Neoplasms

NCT02065687 2021-09-30

Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

Phase 2/3 Unknown

469 enrolled 16 charts

Gynecologic

Endometrial Adenocarcinoma

NCT02394652 2021-04-21

The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial

Phase 2 Completed

16 enrolled

Gynecologic

Adenocarcinoma, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Carcinoma, Adenosquamous

NCT02050009 2019-02-20

Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 1 Withdrawn

Gynecologic

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms

NCT03538704 2018-05-29

ECFerSp

Phase NA Unknown

80 enrolled

Gynecologic

Recurrence, Endometrial Neoplasms

NCT01579812 2018-05-25

Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients

Phase 2 Completed

90 enrolled 9 charts

Gynecologic

Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

NCT01205672 2017-06-02

Evaluation of the Molecular Effects of Metformin on the Endometrium in Patients With Endometrial Cancer

Phase EARLY_PHASE1 Completed

21 enrolled

Gynecologic

Insulin Resistance, Endometrial Neoplasms

NCT02437812 2017-02-28

Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma

Phase 2 Unknown

30 enrolled

Gynecologic

Carcinoma, Ovarian Epithelial

NCT02990728 2016-12-13

Mirena® ± Metformin as Fertility-preserving Treatment for Young Asian Women With Early Endometrial Cancer

Phase 2 Unknown

120 enrolled

Gynecologic

Endometrial Neoplasms

NCT02042495 2016-08-30

Endometrial Cancer Biomarker Changes Following Exposure to Metformin

Phase 2 Withdrawn

Gynecologic

Endometrial Neoplasms

NCT02872818 2016-08-23

Apoptotic Signaling Pathways in Rats With Endometrial Hyperplasia

Phase 4 Completed

40 enrolled

Gynecologic

Endometrial Hyperplasia, Endometrial Neoplasms

NCT01911247 2013-07-30

Preoperative Window Study of Metformin for the Treatment of Endometrial Cancer

Phase EARLY_PHASE1 Completed

28 enrolled

Gynecologic

Endometrial Neoplasms

NCT00659568 2013-05-30

Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma

Phase 1 Completed

28 enrolled

BreastDermatologicGenitourinaryGynecologicLymphoidOther hematologic neoplasmThoracic

Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Renal Cell, Hodgkin Disease, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Endometrial Neoplasms, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Small Cell Lung Carcinoma