Clinical Trials

Phase 1 Active not recruiting

Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Endometrial Neoplasms

NCT06607185 2026-05-26

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

750 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT05919264 2026-05-12

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Phase 1/2 Recruiting

595 enrolled

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Craniopharyngioma, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT01081262 2026-04-30

Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer

Phase 3 Active not recruiting

50 enrolled 13 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT04615013 2026-04-16

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Phase 1 Recruiting

24 enrolled

Cervical Esophagus Adenocarcinoma

NCT04847063 2026-04-14

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Phase 1 Recruiting

60 enrolled

Phase 1 Active not recruiting

Appendiceal Neoplasms, Gastrointestinal Neoplasms, Necrosis, Ovarian Neoplasms, Peritoneal Neoplasms, Colorectal Neoplasms

NCT05891171 2026-03-31

ARC-25

40 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms

NCT07453394 2026-03-06

QLS5132 Combination Therapy in Advanced Solid Tumors

Phase 1/2 Not yet recruiting

626 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT04329494 2025-12-10

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Phase 1 Recruiting

49 enrolled

Appendiceal Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT06840002 2025-09-30

A Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian Cancer

Phase 1/2 Recruiting

150 enrolled

Ovarian Neoplasms

NCT00766142 2025-08-29

COCHISE

18 enrolled 9 charts

Colonic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05007106 2025-08-14

KEYVIBE-005

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

613 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT03314935 2025-08-12

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

Phase 1/2 Completed

149 enrolled 35 charts

BreastDermatologicGenitourinaryGynecologicThoracic

Biliary Tract Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT06990516 2025-05-25

SHR - A1811 Injection in the Treatment of Platinum-sensitive Recurrent Ovarian Cancer

Phase 1/2 Not yet recruiting

90 enrolled

Ovarian Neoplasms

NCT03197584 2025-02-21

QUILT-3.051: NANT Ovarian Cancer Vaccine: Combination Immunotherapy in Subjects With Epithelial Ovarian Cancer Who Have Progressed on or After Standard-of-care (SoC) Therapy

Phase 1/2 Withdrawn

Ovarian Neoplasms

NCT02009449 2024-11-15

IVY

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

353 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT03172416 2024-05-29

PIPAC

Phase 1 Active not recruiting

21 enrolled

Peritoneal Neoplasms, Stomach Neoplasms

NCT04840264 2024-03-18

Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel Obstruction

Phase 2 Recruiting

79 enrolled

Peritoneal Neoplasms

NCT03287375 2022-10-07

PIPAC-OPC2

143 enrolled

Peritoneal Neoplasms

NCT03280511 2022-10-06

Adjuvant Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in Resected High Risk Colon Cancer Patients

Phase 2 Recruiting

60 enrolled

Colonic Neoplasms, Peritoneal Neoplasms

NCT02833753 2022-05-31

Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI

14 enrolled

Appendiceal Neoplasms, Peritoneal Neoplasms, Colorectal Neoplasms

NCT02231086 2021-09-16

COLOPEC

Phase 3 Completed

204 enrolled 7 charts

Peritoneal Neoplasms, Colorectal Neoplasms

NCT04595929 2020-11-25

GASPACCO

Phase NA Recruiting

304 enrolled

Peritoneal Neoplasms, Stomach Neoplasms

NCT02604784 2020-09-17

PI-CaP

Phase 1/2 Completed

105 enrolled

Peritoneal Neoplasms

NCT02658214 2020-08-20

Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors

BreastGastrointestinalGynecologicHead & NeckThoracic

32 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Carcinoma, Pancreatic Ductal, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT03161041 2018-11-14

Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis French Part of the Main Bev-IP Study

Phase 2 Withdrawn

Peritoneal Neoplasms

NCT01936974 2018-02-20

PGA

7 enrolled 1 chart

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT01504256 2018-01-23

CatuNeo

42 enrolled

Adenocarcinoma, Peritoneal Neoplasms

NCT02320448 2017-09-12

Treating Peritoneal Carcinomatosis With PIPAC

35 enrolled

Peritoneal Neoplasms

NCT00352755 2016-12-13

A Phase II Study of Surgical Debulking With Peritonectomy and Biweekly Intraperitoneal 5FU With Systemic Oxaliplatin/5FU/Leucovorin in Patients With Pseudomyxoma Peritonei or Peritoneal Carcinomatosis

18 enrolled 8 charts

Peritoneal Neoplasms

NCT00769405 2016-08-30

Systemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer

Phase 3 Completed

264 enrolled

Colonic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00313612 2015-11-27

Oxaliplatin and Topotecan in Advance Ovarian Cancer

39 enrolled 7 charts

Carcinoma, Ovarian Epithelial

NCT00057863 2015-11-17

Oxaliplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Cervical Cancer

35 enrolled 9 charts

Uterine Cervical Neoplasms

NCT01481701 2014-10-15

A Trial Evaluating Efficacy and Safety of Oxaliplatin With 5-Fluorouracil in Patients With Recurrent Ovarian Carcinoma

90 enrolled

Ovarian Neoplasms, Recurrence

NCT00004206 2014-06-24

Oxaliplatin and Fluorouracil in Treating Patients With Recurrent Ovarian Cancer

Phase 2 Unknown

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00418093 2014-06-19

Oxaliplatin, Gemcitabine and Bevacizumab in Women With Recurrent Mullerian Carcinoma

19 enrolled 10 charts

BreastGastrointestinalGynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT01233505 2014-04-02

Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors

Phase 1 Terminated

16 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Colonic Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT00071929 2013-06-24

Oxaliplatin in Treating Patients With Persistent or Recurrent Endometrial Cancer

Endometrial Neoplasms

NCT00005836 2013-06-21

Oxaliplatin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Has Not Responded to Platinum- Based Chemotherapy

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00005837 2013-06-21

Oxaliplatin in Treating Patients With Recurrent or Refractory Cervical Cancer

Uterine Cervical Neoplasms

NCT00091182 2013-06-05

Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment

CNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

180 enrolled

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Carcinoma, Renal Cell, Colonic Neoplasms, Nasopharyngeal Neoplasms, Neuroblastoma, Rectal Neoplasms, Osteosarcoma, Teratoma, Testicular Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Adrenocortical Carcinoma, Optic Nerve Glioma

NCT00296816 2012-08-23

TEACO

132 enrolled 17 charts

Ovarian Neoplasms

NCT00005860 2011-04-26

Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum