Clinical Trials Browser

Phase 2 × Topotecan × Gynecologic × Clear all

NCT04739800 2026-04-13

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Phase 2 Active not recruiting

120 enrolled 19 charts

GenitourinaryGynecologic

Fallopian Tube Mucinous Adenocarcinoma

NCT02364713 2025-12-11

MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer

Phase 2 Terminated

17 enrolled 14 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT05613088 2025-10-20

A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Phase 2 Completed

106 enrolled 23 charts

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT02569957 2025-05-04

Effect of Acetylcysteine With Topotecan Hydrochloride on the Tumor Microenvironment in Patients With Persistent or Recurrent High Grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Phase 2 Terminated

1 enrolled 5 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT02312245 2024-12-05

Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Phase 2 Completed

13 enrolled 14 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT01696032 2024-08-27

SGI-110

Phase 2 Completed

120 enrolled 22 charts

Ovarian Neoplasms

NCT06548763 2024-08-12

Oral Topotecan With Toripalimab for Patients With Endometrial Cancer

Phase 2 Not yet recruiting

Endometrial Neoplasms

NCT05295589 2023-09-26

Comparing Standard of Care Chemotherapy Treatment to the Combination of Copanlisib and Olaparib for Recurrent Platinum Resistant Ovarian Cancer That Has Progressed Through PARP Inhibitor Therapy

Phase 2 Withdrawn

Platinum-Refractory Fallopian Tube Carcinoma

NCT02822157 2021-01-29

CLIO

Phase 2 Unknown

Carcinoma, Ovarian Epithelial

NCT01266447 2019-08-08

Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer

Phase 2 Completed

27 enrolled 11 charts

Uterine Cervical Neoplasms

NCT00087126 2019-01-08

Topotecan in Treating Women With Persistent or Recurrent Cervical Cancer

Phase 2 Completed

27 enrolled 6 charts

Uterine Cervical Neoplasms

NCT00114166 2018-07-24

Topotecan in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2 Completed

81 enrolled 10 charts

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00005029 2018-04-12

Topotecan in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal Cancer

Phase 2 Terminated

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00257816 2018-02-05

Weekly IV Topotecan and Cisplatin With Radiation in Cervical Carcinoma

Phase 2 Completed

Uterine Cervical Neoplasms

NCT00004221 2017-08-09

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage III Ovarian Cancer

Phase 2 Terminated

Ovarian Neoplasms

NCT00061308 2017-06-09

Second-line Intravenous Treatment For Recurrent Platinum-Sensitive Ovarian, Fallopian, Or Peritoneal Cancer

Phase 2 Completed

Fallopian Tube Neoplasms, Neoplasms, Ovarian Neoplasms

NCT00314678 2016-12-08

Cisplatin Induction With Paclitaxel Consolidation for Stage III-IV Epithelial Ovarian and Primary Peritoneal Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial

NCT02107378 2016-11-30

Efficacy of DCVAC/OvCa Plus Standard of Care in Relapsed Platinum Resistant Epithelial Ovarian Carcinoma

Phase 2 Terminated

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Recurrence

NCT01630018 2016-09-22

Belotecan Versus Topotecan for Recurrent Ovarian Cancer: A Randomized, Open-label, Parallel-group Phase IIb Trial

Phase 2 Completed

Carcinoma, Ovarian Epithelial

NCT02348398 2016-08-16

Phase II Study of Pazopanib and Topotecan in Cervical Cancer

Phase 2 Withdrawn

Uterine Cervical Neoplasms

NCT01003938 2016-06-30

Topotecan With Erlotinib for Topotecan Pretreated Ovarian Cancer

Phase 2 Terminated

6 enrolled 7 charts

Ovarian Neoplasms

NCT00313612 2015-11-27

Oxaliplatin and Topotecan in Advance Ovarian Cancer

Phase 2 Terminated

39 enrolled 7 charts

Carcinoma, Ovarian Epithelial

NCT01121406 2015-08-13

BI 6727 (Volasertib) Randomised Trial in Ovarian Cancer

Phase 2 Completed

110 enrolled 32 charts

Ovarian Neoplasms

NCT00072267 2015-07-23

UCN-01 and Topotecan in Treating Patients With Recurrent, Persistent, or Progressive Advanced Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00343044 2015-05-15

Ph II Study of Wkly Topotecan + Bevacizumab in Plat. Resistant/Recurrent Gyn Cancers

Phase 2 Completed

40 enrolled 10 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00548418 2014-08-01

Topotecan, Cisplatin and Bevacizumab for Recurrent/Persistent Cervical Cancer

Phase 2 Completed

27 enrolled 14 charts

Uterine Cervical Neoplasms

NCT00170677 2014-05-14

Topotecan Weekly Versus Topotecan Day 1-5 in Patient With Platin-resistant Ovarian Cancer

Phase 2 Completed

Ovarian Neoplasms

NCT00436644 2014-04-16

Lapatinib and Topotecan in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Did Not Respond to Cisplatin or Carboplatin

Phase 2 Completed

18 enrolled 10 charts

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00003065 2014-01-06

Topotecan and Paclitaxel in Treating Patients With Recurrent or Metastatic Cancer of the Cervix

Phase 2 Completed

Uterine Cervical Neoplasms

NCT00003733 2013-09-20

Sequential Chemotherapy in Treating Patients With Residual Disease Following Surgery for Stage IIB, Stage III, or Stage IV Ovarian Cancer

Phase 2 Unknown

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00003732 2013-08-12

Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00014690 2013-08-02

ZD9331 With or Without Topotecan in Treating Patients With Refractory or Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00002515 2013-06-24

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

Phase 2 Completed

CNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther solid neoplasmSarcoma

Testicular Germ Cell Tumor, Burkitt Lymphoma, Chondrosarcoma, Fibrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Sarcoma, Osteosarcoma, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Dendritic Cell Sarcoma, Interdigitating, Desmoplastic Small Round Cell Tumor

NCT00276796 2013-05-27

Paclitaxel, Topotecan, and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer

Phase 2 Completed

Uterine Cervical Neoplasms

NCT00003944 2013-04-17

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00316173 2012-11-27

Second-Line Therapy Study For Potentially Platinum-Sensitive Relapsed Ovarian Cancer

Phase 2 Completed

77 enrolled 14 charts

Ovarian Neoplasms, Recurrence

NCT00005051 2012-11-09

Combination Chemotherapy in Treating Patients With Advanced Ovarian Epithelial Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00267488 2012-07-11

Intravenous Weekly Topotecan In Subjects With Recurrent Or Persistent Endometrial Cancer

Phase 2 Completed

70 enrolled 9 charts

Endometrial Neoplasms

NCT00231855 2012-04-24

Efficacy Study of Weekly Taxotere and Topotecan for Recurrent Gynecologic (GYN) Cancers

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Recurrence, Uterine Neoplasms

NCT00193297 2011-05-03

Topotecan Plus Paclitaxel and Carboplatin in the Initial Treatment of Advanced Ovarian and Primary Peritoneal Carcinoma

Phase 2 Completed

Ovarian Neoplasms

NCT00189566 2011-02-25

Taxol® in Monotherapy or in Combination With Topotecan or Carboplatin in Patients With Epithelial Ovarian Cancer in Early Relapse

Phase 2 Completed

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00217555 2010-09-21

Gemcitabine and Topotecan in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00826891 2009-01-22

Study of Cisplatin in Cervical Cancer Stage IVB

Phase 2 Unknown

Uterine Cervical Neoplasms

NCT00194935 2006-09-13

Weekly Topotecan Therapy in Patients With Ovarian Cancer

Phase 2 Terminated

Ovarian Neoplasms