Clinical Trials Browser

Phase 1 × Completed × Gynecologic × Clear all

Esophageal Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms

NCT04881045 2026-06-02

Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms

NCT04354246 2026-05-12

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Phase 1 Completed

94 enrolled

GastrointestinalGynecologicHead & NeckPlasma cellThoracic

Squamous Cell Carcinoma of Head and Neck, Colonic Neoplasms, Lung Neoplasms, Multiple Myeloma, Ovarian Neoplasms, Neoplasms, Plasma Cell

NCT04739527 2026-05-01

ALISON

Phase 1 Completed

17 enrolled

Gynecologic

Ovarian Neoplasms

NCT03732768 2026-04-17

Study of Radspherin® in Recurrent Ovarian Cancer Subjects With Peritoneal Carcinomatosis

Phase 1 Completed

21 enrolled

Gynecologic

Ovarian Neoplasms, Peritoneal Neoplasms

NCT01352962 2026-04-14

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

Phase 1 Completed

18 enrolled

GastrointestinalGenitourinaryGynecologicThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Ureteral Neoplasms, Urethral Neoplasms

NCT06108479 2026-03-18

Study of DF6215 in Patients With Advanced Solid Tumors

Phase 1 Completed

35 enrolled

DermatologicGenitourinaryGynecologicHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms

NCT06894771 2026-03-16

MK-4700-001

Phase 1 Completed

5 enrolled

BreastDermatologicGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Melanoma, Neoplasms, Triple Negative Breast Neoplasms

NCT03239145 2026-03-12

Pembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid Tumor

Phase 1 Completed

62 enrolled 17 charts

DermatologicGastrointestinalGenitourinaryGynecologic

Kidney Neoplasms, Melanoma, Ovarian Neoplasms, Colorectal Neoplasms

NCT02195973 2026-02-09

Phase IB Trial of LDE225 and Paclitaxel in Recurrent Ovarian Cancer

Phase 1 Completed

15 enrolled

Gynecologic

Ovarian Neoplasms

NCT02405221 2026-01-29

Safety and Feasibility of TA-CIN Vaccine in HPV16 Associated Cervical Cancer

Phase 1 Completed

15 enrolled 16 charts

Gynecologic

Uterine Cervical Neoplasms

NCT02407509 2026-01-29

RAF/MEK

Phase 1 Completed

104 enrolled

GynecologicPlasma cellThoracic

Lung Neoplasms, Multiple Myeloma, Ovarian Neoplasms

NCT04640480 2026-01-27

Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumors

Phase 1 Completed

21 enrolled

BreastGastrointestinalGynecologicHead & NeckThoracic

Breast Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Small Cell Lung Carcinoma

NCT05360680 2026-01-22

A Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic Cancers

Phase 1 Completed

42 enrolled

GastrointestinalGenitourinaryGynecologic

Wilms Tumor, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT03578406 2026-01-21

HPV-E6-Specific Anti-PD1 TCR-T Cells in the Treatment of HPV-Positive NHSCC or Cervical Cancer

Phase 1 Completed

9 enrolled

GynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Uterine Cervical Neoplasms

NCT01273168 2025-12-23

Endoxifen in Adults With Hormone Receptor Positive Solid Tumors

Phase 1 Completed

40 enrolled

BreastGynecologicSarcoma

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Uterine Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT05483933 2025-12-23

Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers

Phase 1 Completed

86 enrolled 17 charts

Gynecologic

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT06846099 2025-12-23

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903

Phase 1 Completed

69 enrolled

BreastGynecologic

Breast Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT03245892 2025-12-17

A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer

Phase 1 Completed

27 enrolled

Gynecologic

High Grade Serous Ovarian

NCT06549816 2025-12-15

A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors

Phase 1 Completed

6 enrolled

GastrointestinalGynecologicHead & NeckThoracic

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms

NCT03839524 2025-11-14

A Trial Evaluating TG4050 in Ovarian Carcinoma.

Phase 1 Completed

64 enrolled 14 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT03738228 2025-11-12

Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer

Phase 1 Completed

40 enrolled 17 charts

Gynecologic

Uterine Cervical Neoplasms

NCT03325634 2025-10-23

Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Primary Ovarian or Uterine Cancer

Phase 1 Completed

15 enrolled

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT02159989 2025-10-20

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Phase 1 Completed

83 enrolled 21 charts

GastrointestinalGynecologic

Fibrolamellar hepatocellular carcinoma, Adenoma, Islet Cell, Neoplasm Metastasis, Ovarian Neoplasms

NCT05293496 2025-10-14

A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors

Phase 1 Completed

31 enrolled

DermatologicGastrointestinalGenitourinaryGynecologic

Carcinoma, Ovarian Epithelial, Carcinoma, Renal Cell, Liver Neoplasms, Melanoma, Carcinoma, Pancreatic Ductal, Prostatic Neoplasms, Castration-Resistant

NCT04344795 2025-09-12

Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors

Phase 1 Completed

89 enrolled

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Colorectal Neoplasms, Endometrial Neoplasms

NCT04853017 2025-09-05

AMPLIFY-201

Phase 1 Completed

25 enrolled 15 charts

GastrointestinalGynecologicThoracic

Bile Duct Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gallbladder Neoplasms, Ovarian Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma, Neoplasm, Residual

NCT03085225 2025-09-04

TRAMUNE

Phase 1 Completed

40 enrolled 23 charts

GynecologicSarcoma

Ovarian Neoplasms, Sarcoma

NCT04772989 2025-08-28

ARC-12

Phase 1 Completed

94 enrolled

DermatologicGastrointestinalGynecologicLymphoidPlasma cellThoracic

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Multiple Myeloma, Stomach Neoplasms, Lymphoma, Large B-Cell, Diffuse

NCT03748186 2025-08-20

Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers

Phase 1 Completed

136 enrolled

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Carcinoma, Endometrioid

NCT06165614 2025-08-19

Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya

Phase 1 Completed

17 enrolled

GynecologicOther neoplasm

Uterine Cervical Dysplasia, Uterine Cervical Neoplasms, Precancerous Conditions

NCT06263582 2025-08-19

Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya

Phase 1 Completed

12 enrolled 18 charts

GynecologicLymphoid

Carcinoma in Situ, Uterine Cervical Dysplasia, Uterine Cervical Neoplasms, Lymphoma, Follicular

NCT05585034 2025-08-07

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

Phase 1 Completed

60 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT06048367 2025-08-03

CNSI-Fe(II)

Phase 1 Completed

19 enrolled 47 charts

BreastGastrointestinalGynecologicHead & NeckThoracic

Breast Neoplasms, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms

NCT03199586 2025-07-20

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

Phase 1 Completed

23 enrolled

BreastGastrointestinalGenitourinaryGynecologicThoracic

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT04242199 2025-07-14

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Phase 1 Completed

182 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Nasopharyngeal Carcinoma, Esophageal Squamous Cell Carcinoma, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Mesothelioma, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma

NCT04580485 2025-07-11

INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors

Phase 1 Completed

54 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Ovarian Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT01226316 2025-06-29

Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules

Phase 1 Completed

285 enrolled

BreastGynecologic

Breast Neoplasms, Uterine Cervical Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Endometrial Neoplasms

NCT02159716 2025-06-29

CART-meso in Mesothelin Expressing Cancers

Phase 1 Completed

19 enrolled

Gynecologic

Carcinoma, Ovarian Epithelial, Adenocarcinoma

NCT04608409 2025-06-29

Dose Escalation of Lapatinib With Paclitaxel in Ovarian Cancer

Phase 1 Completed

16 enrolled 14 charts

Gynecologic

Ovarian Neoplasms

NCT05788484 2025-06-15

A Study of CDX-585 in Patients With Advanced Malignancies

Phase 1 Completed

20 enrolled

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT05567601 2025-06-05

Doxil/Caelyx BE Study

Phase 1 Completed

36 enrolled

BreastGynecologicPlasma cellSarcoma

AIDS-related Kaposi sarcoma, Breast Neoplasms, Multiple Myeloma, Ovarian Neoplasms

NCT04811196 2025-05-29

A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients

Phase 1 Completed

56 enrolled

GynecologicSarcoma

Leiomyosarcoma, Sarcoma, Sarcoma, Endometrial Stromal, Neurofibrosarcoma

NCT02672098 2025-05-22

Hyperthermic Intraperitoneal Chemotherapy for Recurrent Ovarian Cancer

Phase 1 Completed

3 enrolled

Gynecologic

Ovarian Neoplasms

NCT03508570 2025-05-22

Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis

Phase 1 Completed

26 enrolled

Gynecologic

Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, Endometrial Neoplasms

NCT03784378 2025-05-15

Continued Access to RXDX-105

Phase 1 Completed

3 enrolled

GynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms

NCT00329589 2025-05-02

A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients

Phase 1 Completed

54 enrolled

CNSGynecologicHead & Neck

Brain Neoplasms, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Central Nervous System Neoplasms

NCT00437372 2025-05-02

Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients

Phase 1 Completed

39 enrolled

GynecologicHead & NeckThoracic

Head and Neck Neoplasms, Neoplasms, Nervous System Neoplasms, Pelvic Neoplasms, Thoracic Neoplasms

NCT03054298 2025-04-29

CAR T Cells in Mesothelin Expressing Cancers

Phase 1 Completed

65 enrolled 14 charts

GynecologicOther solid neoplasmThoracic

Adenocarcinoma of Lung, Mesothelioma, Malignant, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT04774952 2025-04-15

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

Phase 1 Completed

58 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

Clinical Trials

PIFA

Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

ALISON

Study of Radspherin® in Recurrent Ovarian Cancer Subjects With Peritoneal Carcinomatosis

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

Study of DF6215 in Patients With Advanced Solid Tumors

MK-4700-001

Pembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid Tumor

Phase IB Trial of LDE225 and Paclitaxel in Recurrent Ovarian Cancer

Safety and Feasibility of TA-CIN Vaccine in HPV16 Associated Cervical Cancer

RAF/MEK

Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumors

A Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic Cancers

HPV-E6-Specific Anti-PD1 TCR-T Cells in the Treatment of HPV-Positive NHSCC or Cervical Cancer

Endoxifen in Adults With Hormone Receptor Positive Solid Tumors

Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903

A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer

A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors

A Trial Evaluating TG4050 in Ovarian Carcinoma.

Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer

Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Primary Ovarian or Uterine Cancer

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors

Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors

AMPLIFY-201

TRAMUNE

ARC-12

Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers

Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya

Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

CNSI-Fe(II)

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors

Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules

CART-meso in Mesothelin Expressing Cancers

Dose Escalation of Lapatinib With Paclitaxel in Ovarian Cancer

A Study of CDX-585 in Patients With Advanced Malignancies

Doxil/Caelyx BE Study

A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients

Hyperthermic Intraperitoneal Chemotherapy for Recurrent Ovarian Cancer

Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis

Continued Access to RXDX-105

A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients

Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients

CAR T Cells in Mesothelin Expressing Cancers

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors