Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 1Completed 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 6Head & Neck 2Gastrointestinal 2Thoracic 1Gynecologic 1Genitourinary 1Dermatologic 1

Conditions

Squamous Cell Carcinoma of Head and Neck 88Head and Neck Neoplasms 42Carcinoma, Non-Small-Cell Lung 32Melanoma 27Carcinoma, Renal Cell 24Colorectal Neoplasms 18Carcinoma, Transitional Cell 16Carcinoma, Hepatocellular 14Ovarian Neoplasms 13Neoplasm Metastasis 13Carcinoma, Squamous Cell 13Triple Negative Breast Neoplasms 11Stomach Neoplasms 11Carcinoma, Merkel Cell 11Uterine Cervical Neoplasms 10Pancreatic Neoplasms 10Nasopharyngeal Carcinoma 10Oropharyngeal Neoplasms 8Thyroid Neoplasms 7Urinary Bladder Neoplasms 6Small Cell Lung Carcinoma 6Sarcoma 6Recurrence 6Breast Neoplasms 6Mouth Neoplasms 5Lymphoma 5Lung Neoplasms 5Esophageal Neoplasms 5Endometrial Neoplasms 5Salivary Gland Neoplasms 4

Interventions

regorafenib 2Peripheral Blood Stem Cell Transplantation 2Oxaliplatin 2Nivolumab 2Filgrastim 2Cisplatin 2Bevacizumab 2vocimagene amiretrorepvec 1tovorafenib 1pembrolizumab 1entinostat 1aflibercept 1Thiotepa 1Thalidomide 1Temozolomide 1Tamoxifen 1Radiotherapy 1Quality of Life 1Patient Reported Outcome Measures 1Paclitaxel 1NEO212 1Molecular Diagnostic Techniques 1Magnetic Resonance Spectroscopy 1Irinotecan 1Ipilimumab 1Immunotherapy 1IFL protocol 1Flucytosine 1Fentanyl 1Etoposide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Astrocytoma × Nivolumab × Head & Neck × Clear all
NCT06047379 2026-03-02

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Neonc Technologies, Inc.

Phase 1/2 Recruiting
134 enrolled
CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Central Nervous System Neoplasms, Small Cell Lung Carcinoma

NCT04704154 2025-04-18

A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors

Bayer

Phase 2 Completed
175 enrolled 20 charts
CNSGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Glioblastoma

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