Announcements Trials
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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Head & Neck 1Gynecologic 1Endocrine 1Breast 1

Conditions

Squamous Cell Carcinoma of Head and Neck 6Uterine Cervical Neoplasms 5Head and Neck Neoplasms 5Vaginal Neoplasms 4Penile Neoplasms 4Oropharyngeal Neoplasms 4Neoplasm Metastasis 4Anus Neoplasms 4Stomach Neoplasms 3Melanoma 3Carcinoma, Squamous Cell 3Carcinoma, Non-Small-Cell Lung 3Vulvar Neoplasms 2Thyroid Neoplasms 2Thyroid Carcinoma, Anaplastic 2Small Cell Lung Carcinoma 2Salivary Gland Neoplasms 2Pancreatic Neoplasms 2Ovarian Neoplasms 2Colorectal Neoplasms 2Carcinoma, Renal Cell 2Carcinoma, Merkel Cell 2Carcinoma, Hepatocellular 2Urinary Bladder Neoplasms 1Triple Negative Breast Neoplasms 1Tongue Neoplasms 1Thyroid Cancer, Papillary 1Testicular Neoplasms 1Testicular Germ Cell Tumor 1Sarcoma 1

Interventions

Cyclophosphamide 2fludarabine 1cc-486 1aldesleukin 1Surveys and Questionnaires 1Quality of Life 1Psychology, Positive 1Patient Reported Outcome Measures 1Observation 1Nivolumab 1Molecular Diagnostic Techniques 1Methods 1Ipilimumab 1Injections 1Immunotherapy 1Genetic Testing 1Etoposide 1Drug Therapy 1Calcifediol 1CTLA-4 Antigen 1Biological Therapy 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Bone Neoplasms × aldesleukin × Head & Neck × Clear all
NCT03449108 2026-05-22

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
30 enrolled
BreastEndocrineGynecologicHead & NeckSarcoma

Bone Neoplasms, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Giant Cell Tumor of Bone, Histiocytoma, Malignant Fibrous, Triple Negative Breast Neoplasms, Thyroid Carcinoma, Anaplastic

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