Announcements Trials
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Phase

Phase 2 3Phase NA 2Phase 1 2Phase 1/2 1

Status

Withdrawn 1Terminated 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2

Conditions

Squamous Cell Carcinoma of Head and Neck 389Head and Neck Neoplasms 340Carcinoma, Non-Small-Cell Lung 230Melanoma 155Colorectal Neoplasms 152Breast Neoplasms 138Ovarian Neoplasms 125Neoplasms 103Stomach Neoplasms 101Carcinoma, Renal Cell 101Neoplasm Metastasis 94Pancreatic Neoplasms 93Lung Neoplasms 87Uterine Cervical Neoplasms 81Triple Negative Breast Neoplasms 75Esophageal Neoplasms 75Prostatic Neoplasms 70Urinary Bladder Neoplasms 69Thyroid Neoplasms 62Carcinoma, Squamous Cell 57Carcinoma, Hepatocellular 57Sarcoma 54Endometrial Neoplasms 54Carcinoma, Transitional Cell 54Small Cell Lung Carcinoma 50Salivary Gland Neoplasms 49Colonic Neoplasms 41Nasopharyngeal Carcinoma 38Mouth Neoplasms 37Kidney Neoplasms 34

Interventions

Metformin 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Erythroplasia × Head & Neck × Clear all
NCT05536037 2025-05-15

Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

Thomas Jefferson University

Phase 1 Terminated
4 enrolled
Head & Neck

Erythroplasia, Leukoplakia, Mouth Neoplasms

NCT03939364 2021-10-19

This Study is to Evaluate the Safety and Pharmacokinetics of SBS-101 in Patients With Oral Premalignant Lesions

Skyline Biosciences

Phase 1 Withdrawn
Head & Neck

Erythroplasia, Leukoplakia, Oral

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