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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

OTHER 8INDUSTRY 3OTHER_GOV 1NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 1

Conditions

Squamous Cell Carcinoma of Head and Neck 114Head and Neck Neoplasms 98Thyroid Neoplasms 55Salivary Gland Neoplasms 55Oropharyngeal Neoplasms 35Mouth Neoplasms 33Tongue Neoplasms 30Thyroid Cancer, Papillary 26Laryngeal Neoplasms 26Adenocarcinoma, Follicular 23Nasopharyngeal Neoplasms 22Carcinoma, Non-Small-Cell Lung 22Breast Neoplasms 21Hypopharyngeal Neoplasms 20Uterine Cervical Neoplasms 19Colonic Neoplasms 19Carcinoma, Medullary 16Rectal Neoplasms 15Pancreatic Neoplasms 15Esthesioneuroblastoma, Olfactory 15Esophageal Neoplasms 15Anus Neoplasms 15Neoplasms 14Lung Neoplasms 14Thyroid Carcinoma, Anaplastic 13Stomach Neoplasms 13Melanoma 13Carcinoma, Renal Cell 12Urinary Bladder Neoplasms 11Prostatic Neoplasms 11

Interventions

Metformin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Erythroplasia × Head & Neck × Clear all
NCT02581137 2026-04-13

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

National Cancer Institute (NCI)

Phase 2 Active not recruiting
26 enrolled 10 charts
Head & Neck

Erythroplasia, Hyperplasia, Leukoplakia, Oral, Mouth Neoplasms

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