Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Terminated 1Recruiting 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 8Other hematologic neoplasm 5Lymphoid 4Classical hematology 3Thoracic 2Head & Neck 2Gastrointestinal 2Sarcoma 1Endocrine 1Dermatologic 1CNS 1

Conditions

Head and Neck Neoplasms 2603Squamous Cell Carcinoma of Head and Neck 1880Thyroid Neoplasms 704Nasopharyngeal Carcinoma 627Carcinoma, Non-Small-Cell Lung 477Mouth Neoplasms 424Breast Neoplasms 383Neoplasms 381Oropharyngeal Neoplasms 359Melanoma 339Lung Neoplasms 318Colorectal Neoplasms 307Carcinoma, Squamous Cell 282Neoplasm Metastasis 255Ovarian Neoplasms 254Laryngeal Neoplasms 253Salivary Gland Neoplasms 236Uterine Cervical Neoplasms 234Stomach Neoplasms 223Esophageal Neoplasms 222Nasopharyngeal Neoplasms 221Pancreatic Neoplasms 213Prostatic Neoplasms 203Carcinoma, Renal Cell 201Thyroid Nodule 179Thyroid Cancer, Papillary 178Urinary Bladder Neoplasms 163Sarcoma 160Recurrence 143Hypopharyngeal Neoplasms 143

Interventions

Panitumumab 1PLX8394 1IFL protocol 1Gemcitabine 1Cetuximab 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Histiocytosis × Head & Neck × Clear all
NCT05786924 2026-04-21

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Servier

Phase 1/2 Recruiting
554 enrolled
CNSGastrointestinalHead & NeckMyeloidThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Histiocytosis

NCT02012231 2020-10-19

Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers.

Fore Biotherapeutics

Phase 1 Terminated
5 enrolled
DermatologicEndocrineGastrointestinalHead & NeckMyeloidOther hematologic neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Leukemia, Hairy Cell, Melanoma, Thyroid Neoplasms, Colorectal Neoplasms, Histiocytosis, Cholangiocarcinoma, Thyroid Carcinoma, Anaplastic

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