Clinical Trials Browser

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT06056310 2025-09-29

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)

Phase 1 Terminated

18 enrolled 9 charts

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases

NCT03529422 2025-07-20

Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN

Phase 2 Active not recruiting

18 enrolled 10 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Laryngeal Diseases, Mouth Neoplasms

NCT03109873 2025-04-30

Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer

Phase EARLY_PHASE1 Completed

9 enrolled 6 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Laryngeal Diseases

NCT01185171 2023-05-11

Trial of Induction Chemotherapy With Carboplatin and Paclitaxel, Followed by Concurrent Chemotherapy/Radiation Therapy With ZD1839 (IRESSA), 5-FU, Hydroxyurea, and Twice-Daily Radiation, Followed by Adjuvant ZD1839 Monotherapy in Patients With Locally Advanced Head & Neck Cancer

Phase 2 Completed

70 enrolled 11 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Head and Neck Neoplasms, Laryngeal Diseases

NCT02126969 2023-03-13

A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN

Phase 2 Completed

45 enrolled 13 charts

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases, Neoplasms

NCT01326923 2020-10-09

Induction Chemo Then Concurrent Chemoradiotherapy With Cetuximab in Locally Advanced Head and Neck Squamous Cell Cancer

Phase 2 Terminated

7 enrolled 5 charts

Head & Neck

Laryngeal Diseases

NCT02926573 2018-08-08

GABA

Phase 4 Completed

123 enrolled 13 charts

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases, Pain, Postoperative, Acute Pain

NCT01456143 2018-02-01

Optical Imaging of Head and Neck Cancer

Phase NA Terminated

33 enrolled 9 charts

Head & Neck

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Neoplasms

NCT00101582 2016-09-27

Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer

Phase 3 Completed

188 enrolled 19 charts

Head & NeckOther

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Stomatitis, Xerostomia, Oral Ulcer, Mucositis

NCT01843673 2016-07-06

Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer

Phase NA Completed

16 enrolled 9 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Head and Neck Neoplasms, Laryngeal Diseases

NCT01219673 2015-02-10

Symptom Burden in Head and Neck Cancer

Phase 1/2 Terminated

1 enrolled 2 charts

Head & Neck

cyclopia sequence, Carcinoma, Head and Neck Neoplasms, Laryngeal Diseases

NCT01087970 2014-05-19

A Study for Participants With Recurrent or Metastatic Squamous Cell Head and Neck Cancer

Phase 2 Completed

69 enrolled 15 charts

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases

NCT00589667 2014-04-02

A Phase II Study of Pemetrexed Plus Gemcitabine for Metastatic/Recurrent Head and Neck Cancer (HNSCC)

Phase 2 Completed

26 enrolled 8 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Head and Neck Neoplasms, Laryngeal Diseases

NCT01057589 2013-09-18

A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer

Phase 2 Completed

66 enrolled 11 charts

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases, Thyroid Diseases

NCT00100789 2012-10-01

S0329, Gemcitabine and Paclitaxel in Treating Patients With Persistent, Recurrent, or Metastatic Head and Neck Cancer

Phase 2 Completed

67 enrolled 10 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Neoplasm Metastasis, Recurrence

Clinical Trials

INTERLINK-1

Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy for HPV + Oropharyngeal Cancers

Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION)

Pembrolizumab in Combination With CRT for LA-SCCHN

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)

Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN

Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer

Trial of Induction Chemotherapy With Carboplatin and Paclitaxel, Followed by Concurrent Chemotherapy/Radiation Therapy With ZD1839 (IRESSA), 5-FU, Hydroxyurea, and Twice-Daily Radiation, Followed by Adjuvant ZD1839 Monotherapy in Patients With Locally Advanced Head & Neck Cancer

A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN

Induction Chemo Then Concurrent Chemoradiotherapy With Cetuximab in Locally Advanced Head and Neck Squamous Cell Cancer

GABA

Optical Imaging of Head and Neck Cancer

Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer

Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer

Symptom Burden in Head and Neck Cancer

A Study for Participants With Recurrent or Metastatic Squamous Cell Head and Neck Cancer

A Phase II Study of Pemetrexed Plus Gemcitabine for Metastatic/Recurrent Head and Neck Cancer (HNSCC)

A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer

S0329, Gemcitabine and Paclitaxel in Treating Patients With Persistent, Recurrent, or Metastatic Head and Neck Cancer