Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 25Sarcoma 11Gastrointestinal 10Genitourinary 9Myeloid 8Lymphoid 8Endocrine 3NET 2Head & Neck 2Dermatologic 2Thoracic 1

Conditions

Squamous Cell Carcinoma of Head and Neck 143Head and Neck Neoplasms 121Carcinoma, Non-Small-Cell Lung 51Thyroid Neoplasms 43Melanoma 37Nasopharyngeal Carcinoma 35Mouth Neoplasms 35Ovarian Neoplasms 32Colorectal Neoplasms 31Breast Neoplasms 31Oropharyngeal Neoplasms 30Neoplasm Metastasis 26Uterine Cervical Neoplasms 25Lung Neoplasms 24Carcinoma, Squamous Cell 21Carcinoma, Renal Cell 21Stomach Neoplasms 20Neoplasms 20Carcinoma 19Esophageal Neoplasms 18Pancreatic Neoplasms 17Triple Negative Breast Neoplasms 16Prostatic Neoplasms 16Laryngeal Neoplasms 16Endometrial Neoplasms 16Sarcoma 15Urinary Bladder Neoplasms 14Hypopharyngeal Neoplasms 12Carcinoma, Transitional Cell 12Salivary Gland Neoplasms 11

Interventions

tipifarnib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Medulloblastoma × Head & Neck × 30 days × Clear all
NCT04284774 2026-05-27

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

Phase 2 Active not recruiting
5 enrolled 9 charts
CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Wilms Tumor, Neuroblastoma, Pheochromocytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Thyroid Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT07584499 2026-05-13

MRG003

Sun Yat-sen University

Phase 1 Recruiting
51 enrolled
CNSGenitourinaryHead & NeckSarcoma

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Rhabdoid Tumor

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