Announcements Trials
Browse Landscape

Phase

Phase 2 1Phase 1/2 1

Status

Completed 8Active not recruiting 2Recruiting 1

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 33Sarcoma 13Lymphoid 10Genitourinary 10Gastrointestinal 10Myeloid 9Endocrine 3Head & Neck 2Dermatologic 2Thoracic 1NET 1

Conditions

Squamous Cell Carcinoma of Head and Neck 173Head and Neck Neoplasms 141Thyroid Neoplasms 59Carcinoma, Non-Small-Cell Lung 58Oropharyngeal Neoplasms 48Melanoma 47Nasopharyngeal Carcinoma 45Colorectal Neoplasms 33Mouth Neoplasms 30Carcinoma, Renal Cell 29Breast Neoplasms 27Uterine Cervical Neoplasms 26Neoplasms 26Ovarian Neoplasms 25Stomach Neoplasms 24Carcinoma, Squamous Cell 23Lung Neoplasms 22Esophageal Neoplasms 22Triple Negative Breast Neoplasms 20Neoplasm Metastasis 20Endometrial Neoplasms 20Salivary Gland Neoplasms 19Thyroid Cancer, Papillary 16Pancreatic Neoplasms 16Sarcoma 15Laryngeal Neoplasms 15Urinary Bladder Neoplasms 13Prostatic Neoplasms 13Colonic Neoplasms 13Carcinoma, Transitional Cell 13

Interventions

tipifarnib 1entrectinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Active not recruiting × Medulloblastoma × Head & Neck × Clear all
NCT04284774 2026-05-27

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

Phase 2 Active not recruiting
5 enrolled 9 charts
CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Wilms Tumor, Neuroblastoma, Pheochromocytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Thyroid Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT02650401 2026-03-25

STARTRK-NG

Hoffmann-La Roche

Phase 1/2 Active not recruiting
69 enrolled 1 FDA
CNSEndocrineGenitourinaryHead & NeckSarcoma

Thyroid Cancer, Papillary, Brain Neoplasms, Glioma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Salivary Gland Neoplasms, Sarcoma, Sarcoma, Ewing, Central Nervous System Neoplasms, Nephroma, Mesoblastic

Data powered by HemOnc (CC BY 4.0) Colophon âš¡