Announcements Trials
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Phase

Phase 1/2 9Phase 2 4Phase NA 3Phase 1 3Phase 2/3 2Phase 3 1

Status

Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 6Lymphoid 5Gastrointestinal 5CNS 5Gynecologic 3Dermatologic 3Thoracic 2Plasma cell 2Myeloid 2Head & Neck 2Endocrine 2Sarcoma 1Genitourinary 1

Conditions

Head and Neck Neoplasms 32Squamous Cell Carcinoma of Head and Neck 24Nasopharyngeal Carcinoma 10Mouth Neoplasms 10Thyroid Neoplasms 9Oropharyngeal Neoplasms 9Laryngeal Neoplasms 8Ovarian Neoplasms 5Lung Neoplasms 5Hypopharyngeal Neoplasms 5Colorectal Neoplasms 5Neoplasms 4Neoplasm Metastasis 4Melanoma 4Carcinoma, Squamous Cell 4Carcinoma 4Thyroid Carcinoma, Anaplastic 3Thyroid Cancer, Papillary 3Recurrence 3Neoplasms, Squamous Cell 3Nasopharyngeal Neoplasms 3Hematologic Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Breast Neoplasms 3Uterine Cervical Neoplasms 2Urinary Bladder Neoplasms 2Stomatitis 2Salivary Gland Neoplasms 2Prostatic Neoplasms 2Parathyroid Neoplasms 2

Interventions

trametinib 1dabrafenib 1cobimetinib 1Vemurafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2/3 × Neoplasms by Site × Head & Neck × Clear all
NCT07440290 2026-02-27

DETERMINE

Cancer Research UK

Phase 2/3 Not yet recruiting
30 enrolled
CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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