Announcements Trials
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Phase

Phase 2 4

Status

Completed 2Terminated 1Recruiting 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Head & Neck 4Other neoplasm 1

Conditions

Head and Neck Neoplasms 16Mouth Neoplasms 7Squamous Cell Carcinoma of Head and Neck 4Oropharyngeal Neoplasms 4Laryngeal Neoplasms 4Hypopharyngeal Neoplasms 4Tongue Neoplasms 2Salivary Gland Neoplasms 2Paranasal Sinus Neoplasms 2Nasopharyngeal Neoplasms 2Nasopharyngeal Carcinoma 2Lung Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Carcinoma 2Thyroid Neoplasms 1Thyroid Cancer, Papillary 1Stomatitis 1Recurrence 1Precancerous Conditions 1Pharyngeal Neoplasms 1Papilloma 1Neoplasms 1Mucositis 1Leukoplakia, Oral 1Laryngeal papillomatosis 1Adenocarcinoma, Follicular 1

Interventions

Cisplatin 57Radiotherapy 35Radiotherapy, Intensity-Modulated 30Magnetic Resonance Spectroscopy 24Radiation 21Carboplatin 19pembrolizumab 18Specimen Handling 16Platinum 14Cetuximab 141,2-diaminocyclohexaneplatinum II citrate 14Surveys and Questionnaires 13Paclitaxel 13Biopsy 11Surgical Procedures, Operative 10Fluorouracil 10Docetaxel 9Taxes 8Nivolumab 8Drug Therapy 8Chemoradiotherapy 8durvalumab 7Fluorodeoxyglucose F18 7Observation 6Blood Specimen Collection 6fludarabine 5X-Rays 5Immunohistochemistry 5Cyclophosphamide 5aldesleukin 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × Celecoxib × Head & Neck × Clear all
NCT06997068 2026-05-11

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population

Mayo Clinic

Phase 2 Recruiting
25 enrolled
Head & Neck

Carcinoma, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT04162873 2025-02-12

Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer

University of Utah

Phase 2 Terminated
13 enrolled 36 charts
Head & Neck

Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Paranasal Sinus Neoplasms

NCT00052611 2018-03-29

Celecoxib in Preventing Cancer in Patients With Oral Leukoplakia and/or Head and Neck Dysplasia

Dana-Farber Cancer Institute

Phase 2 Completed
23 enrolled
Head & Neck

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms

NCT00101335 2013-07-11

Celecoxib in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

Fox Chase Cancer Center

Phase 2 Completed
Head & NeckOther neoplasm

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Leukoplakia, Oral, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions, Tongue Neoplasms

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