Clinical Trials

Nasopharyngeal Carcinoma, Recurrence

NCT03082534 2026-01-28

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

78 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Recurrence

NCT04326257 2026-01-08

Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy

20 enrolled 13 charts

Diabetes Mellitus, Insulin-Dependent, 12, Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT04220866 2025-10-29

MK-1454-002

18 enrolled 14 charts

Phase 2 Active not recruiting

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT03383094 2025-10-07

Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

126 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Oropharyngeal Neoplasms, Recurrence

NCT07070479 2025-09-18

Combination Therapy for PD-1 Resistant Recurrent or Metastatic Nasopharyngeal Carcinoma: A Bayesian Adaptive Phase II Trial

208 enrolled

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT04868162 2025-07-08

A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck

116 enrolled

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Recurrence

NCT06892431 2025-03-25

JMT101 Combined With Mitoxantrone Liposome for Nasopharyngeal Cancer

150 enrolled

Nasopharyngeal Neoplasms, Recurrence

NCT06472713 2025-01-13

Clinical Study of Mitoxantrone Hydrochloride Liposome Combined with PD-1 Blockade in Recurrent or Metastatic NPC

32 enrolled

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT06657690 2025-01-10

Irinotecan Liposome Combined with S-1 in PD-1/L1 Inhibitor Refractory Recurrent or Metastatic NPC

56 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT04996758 2024-12-12

Toripalimab and Anlotinib Combination Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma After Failure of at Least One Line of Platinum-Based Chemotherapy (TORAL)

40 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT04396886 2024-05-09

Bintrafusp Alfa in Previously Treated Patients With R/M Non-keratinizing NPC

38 enrolled

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT03723967 2024-04-22

FRAIL-IMMUNE

104 enrolled

Squamous Cell Carcinoma of Head and Neck, Recurrence

NCT06103617 2023-11-18

Safety and Superiority of Penicillamine in Radiosensitization of Recurrent Head and Neck Cancer

10 enrolled

Head and Neck Neoplasms, Recurrence

NCT02624128 2023-11-13

V-CHANCE

39 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT05260671 2023-10-18

Penpulimab in Combination With Cetuximab as First-line Treatment in R/M SCCHN

48 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT06087068 2023-10-17

Thyroxine Replacement Therapy After Lobectomy for Low-risk Papillary Thyroid Carcinoma

140 enrolled

Recurrence, Thyroid Neoplasms

NCT05626829 2023-10-06

Tranilast as a Radiosensitizer in Reradiation of Nasopharyngeal Carcinoma

18 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT01684098 2023-06-22

Safety and Efficacy of FalateScan (Technetium Tc 99m EC20) in Patients With Known Suspected Recurrent or Metastatic Cancer From a Solid Tumor

GastrointestinalGenitourinaryHead & Neck

40 enrolled

Urinary Bladder Neoplasms, Head and Neck Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Recurrence, Testicular Neoplasms

NCT03620123 2022-11-18

OPTIM

54 enrolled

Squamous Cell Carcinoma of Head and Neck, Recurrence

NCT01864772 2022-08-19

ELANFIT

85 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT01606566 2022-02-18

A Study to Evaluate the Safety and Efficacy of Amphinex Induced PCI of Bleomycin for Recurrent Head and Neck Cancer.

26 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasms, Recurrence

NCT02605967 2022-02-10

Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma

122 enrolled 28 charts

Nasopharyngeal Carcinoma, Nasopharyngeal Neoplasms, Recurrence, Disorders of Sex Development

NCT03132038 2022-01-11

NISCAHN

98 enrolled

Neoplasm Metastasis, Recurrence, Salivary Gland Neoplasms

NCT01094405 2021-07-28

Efficacy of Recombinant Epstein-Barr Virus (EBV) Vaccine in Patients With Nasopharyngeal Cancer Who Had Residual EBV DNA Load After Conventional Therapy

25 enrolled

Nasopharyngeal Neoplasms, Recurrence, Epstein-Barr Virus Infections

NCT01620242 2021-03-02

ORL03

31 enrolled

Head and Neck Neoplasms, Recurrence

NCT00768664 2021-02-09

Open-Label Trial Of Oral PF-00299804 By Continuous Dosing In Patients With Recurrent Or Metastatic Head And Neck Squamous Cell Cancer

69 enrolled 18 charts

Head and Neck Neoplasms, Recurrence

NCT02636231 2021-02-03

Endostar for Locally Recurrent Nasopharyngeal Carcinoma

96 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT03887442 2021-01-07

EXTAX

17 enrolled 8 charts

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT02207530 2020-09-29

Phase II Study of MEDI4736 Monotherapy in Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

112 enrolled 20 charts

Head and Neck Neoplasms, Recurrence

NCT02319044 2020-09-29

Phase II Study of MEDI4736, Tremelimumab, and MEDI4736 in Combination w/ Tremelimumab Squamous Cell Carcinoma of the Head and Neck

267 enrolled 27 charts

Head and Neck Neoplasms, Recurrence

NCT02124707 2020-08-12

Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN

14 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT04126460 2019-10-15

RePASS

41 enrolled

Head and Neck Neoplasms, Recurrence

NCT00408252 2019-09-19

Efficacy of SU 011248 in Head And Neck Carcinoma

54 enrolled

Squamous Cell Carcinoma of Head and Neck, Recurrence

NCT02789189 2019-09-06

Nedaplatin Combined With Gemcitabine in the Treatment of Recurrent and/or Metastatic Nasopharyngeal Carcinoma : a Single Arm and Phase Ⅱ Clinical Trail

60 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT01737450 2019-06-24

PIK-ORL

58 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence, Disease Progression

NCT02269943 2018-12-12

Safety and Efficacy of CC-486 in Previously Treated Patients With Locally Advanced or Metastatic Nasopharyngeal Carcinoma

36 enrolled 24 charts