Clinical Trials

33 enrolled

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT06197776 2026-05-11

Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for r/m NPC

Recruiting

50 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT06769698 2026-05-06

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

120 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT03483337 2026-04-14

New MRI Biomarkers in Head and Neck Cancers

Recruiting

200 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence, Thyroid Neoplasms

NCT07423078 2026-04-13

WOLF

87 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT06064877 2026-04-09

FIERCE-HN

410 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Neoplasm Metastasis, Recurrence

NCT05047094 2026-04-06

Alpha Radiation Emitters Device (DaRT) in Combination With Check Point Inhibitor for the Treatment of Recurrent Unresectable or mHNSCC

Phase NA Recruiting

48 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Recurrence, Skin Neoplasms

NCT07501650 2026-03-30

Pembrolizumab Plus Ultrasound-Induced Microbubble Cavitation in Head and Neck Cancer

Phase 1 Recruiting

6 enrolled

Head and Neck Neoplasms, Recurrence

NCT07485296 2026-03-20

POST-BIO

45 enrolled

Squamous Cell Carcinoma of Head and Neck, Recurrence

NCT06868433 2026-03-04

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

Phase 1 Recruiting

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Recurrence

NCT06096038 2026-02-20

Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC

Phase 1/2 Recruiting

33 enrolled

Head and Neck Neoplasms, Neoplasms, Recurrence

NCT06330064 2026-02-12

A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)

DermatologicGastrointestinalGenitourinaryGynecologicHead & Neck

520 enrolled

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Biliary Tract Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Recurrence, Colorectal Neoplasms, Endometrial Neoplasms

NCT06976190 2026-01-20

Magic-C002

446 enrolled

BreastDermatologicGenitourinaryGynecologicHead & NeckLymphoid

Nasopharyngeal Carcinoma, Recurrence

NCT06022029 2025-12-24

ON-5001

Phase 1 Recruiting

168 enrolled

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Bites and Stings, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma in Situ, Uterine Cervical Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence, Skin Neoplasms, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell, Triple Negative Breast Neoplasms

NCT07258979 2025-12-02

A Study of YL201 in Combination With Toripalimab and With or Without Cisplatin in Nasopharyngeal Carcinoma.

Phase 1/2 Recruiting

202 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT07070479 2025-09-18

Combination Therapy for PD-1 Resistant Recurrent or Metastatic Nasopharyngeal Carcinoma: A Bayesian Adaptive Phase II Trial

208 enrolled

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT04868162 2025-07-08

A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck

116 enrolled

Squamous Cell Carcinoma of Head and Neck, Recurrence

NCT06389201 2025-02-18

Pretreatment With HCQ Before Radiotherapy and Chemotherapy in Advanced NPC Patients

Phase NA Recruiting

30 enrolled

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT06472713 2025-01-13

Clinical Study of Mitoxantrone Hydrochloride Liposome Combined with PD-1 Blockade in Recurrent or Metastatic NPC

32 enrolled

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT06657690 2025-01-10

Irinotecan Liposome Combined with S-1 in PD-1/L1 Inhibitor Refractory Recurrent or Metastatic NPC

56 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT06016920 2024-12-17

Safety and Efficacy of VB10.16 and Pembrolizumab in Patients with Head-Neck Squamous Cell Carcinoma

Phase 1/2 Recruiting

51 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT06241599 2024-02-05

A Multi-center, Randomized, Double-blind, Phase II/III Clinical Trial of AK104 or Placebo in Combination With Chemotherapy as Second-line or More Lines for Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)

Phase 2/3 Recruiting

300 enrolled

Nasopharyngeal Carcinoma, Recurrence

NCT05962892 2024-01-30

A Study of Factors Influencing Recurrence After Thermal Ablation of Papillary Thyroid Carcinoma

Recruiting

600 enrolled

EndocrineHead & Neck

Thyroid Cancer, Papillary, Recurrence

NCT05260671 2023-10-18

Penpulimab in Combination With Cetuximab as First-line Treatment in R/M SCCHN

48 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT06087068 2023-10-17

Thyroxine Replacement Therapy After Lobectomy for Low-risk Papillary Thyroid Carcinoma

140 enrolled

Recurrence, Thyroid Neoplasms

NCT06082180 2023-10-13

A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection in Low-risk Papillary Thyroid Cancer

1,199 enrolled

Recurrence, Thyroid Neoplasms

NCT04778956 2021-03-04

Toripalimab Plus Surgery vs Surgery Alone for Resectable Recurrent Nasopharyngeal Carcinoma

218 enrolled