Announcements Trials
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Phase

Phase 2 1Phase 1/2 1Phase 1 1

Status

Active not recruiting 2Terminated 1

Sponsor Class

INDUSTRY 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 236CNS 85Genitourinary 56Gastrointestinal 42Lymphoid 39Other hematologic neoplasm 15Other solid neoplasm 13Myeloid 13Dermatologic 13Gynecologic 8Endocrine 5Thoracic 4Breast 4Head & Neck 3Plasma cell 2Classical hematology 1

Conditions

Head and Neck Neoplasms 2595Squamous Cell Carcinoma of Head and Neck 1875Thyroid Neoplasms 703Nasopharyngeal Carcinoma 626Carcinoma, Non-Small-Cell Lung 475Mouth Neoplasms 424Breast Neoplasms 382Neoplasms 381Oropharyngeal Neoplasms 359Melanoma 339Lung Neoplasms 317Colorectal Neoplasms 305Carcinoma, Squamous Cell 282Neoplasm Metastasis 255Laryngeal Neoplasms 253Ovarian Neoplasms 252Salivary Gland Neoplasms 236Uterine Cervical Neoplasms 232Stomach Neoplasms 223Esophageal Neoplasms 222Nasopharyngeal Neoplasms 220Pancreatic Neoplasms 213Prostatic Neoplasms 202Carcinoma, Renal Cell 200Thyroid Nodule 178Thyroid Cancer, Papillary 178Urinary Bladder Neoplasms 163Sarcoma 160Hypopharyngeal Neoplasms 143Recurrence 142

Interventions

tipifarnib 1entrectinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Sarcoma, Ewing × Head & Neck × Clear all
NCT04284774 2026-05-27

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

Phase 2 Active not recruiting
5 enrolled 9 charts
CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Wilms Tumor, Neuroblastoma, Pheochromocytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Thyroid Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT02650401 2026-03-25

STARTRK-NG

Hoffmann-La Roche

Phase 1/2 Active not recruiting
69 enrolled 1 FDA
CNSEndocrineGenitourinaryHead & NeckSarcoma

Thyroid Cancer, Papillary, Brain Neoplasms, Glioma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Salivary Gland Neoplasms, Sarcoma, Sarcoma, Ewing, Central Nervous System Neoplasms, Nephroma, Mesoblastic

NCT05605522 2025-08-24

A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours

3B Pharmaceuticals GmbH

Phase 1 Terminated
19 enrolled
GastrointestinalGenitourinaryHead & NeckSarcoma

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Prostatic Neoplasms, Sarcoma, Ewing, Stomach Neoplasms, Colorectal Neoplasms

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