Clinical Trials

1,004 enrolled

Gingivitis, Mouth Diseases, Mouth Neoplasms, Periodontitis, Stomatitis, Xerostomia

NCT07020754 2026-01-30

Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial

84 enrolled

Head and Neck Neoplasms, Stomatitis

NCT07247799 2026-01-27

Ozone Therapy for the Treatment of Oral Mucositis in Patients Undergoing Radio and Chemotherapy in the Head and Neck Region

Completed

38 enrolled

Head and Neck Neoplasms, Stomatitis

NCT07199712 2025-11-25

OZOMUC

58 enrolled

Agnosia, Head and Neck Neoplasms, Stomatitis

NCT07069153 2025-11-17

LOMUC

Head & NeckOther hematologic neoplasm

40 enrolled

Cancer Pain, Head and Neck Neoplasms, Stomatitis, Hematologic Neoplasms

NCT06251050 2025-05-30

A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy

Phase 1/2 Completed

175 enrolled

Phase EARLY_PHASE1 Completed

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Head and Neck Neoplasms, Stomatitis

NCT05278260 2025-05-14

Hydrogen-rich Water and Treatment of Mucositis Caused by Radiation Therapy in Head and Neck Cancer Patients

24 enrolled

Head and Neck Neoplasms, Stomatitis

NCT06122636 2025-04-03

HNC

62 enrolled

Dental Plaque, Head and Neck Neoplasms, Periodontal Diseases, Stomatitis, Xerostomia, Dysbiosis

NCT04382079 2025-03-05

Honey Products for Cancer Patients With Oral Mucositis: a Randomized Controlled Trial

75 enrolled

Head and Neck Neoplasms, Stomatitis, Mucositis

NCT03515538 2024-11-04

PREVLAR

53 enrolled 15 charts

Head and Neck Neoplasms, Mouth Neoplasms, Stomatitis, Mucositis

NCT03972527 2024-08-21

Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients

85 enrolled

Head and Neck Neoplasms, Stomatitis, Ulcer

NCT05918224 2024-02-05

Streptococcus Salivarius K12 for Prevention and Treatment of Oral Mucositis in Patients Undergoing Radiotherapy

160 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Stomatitis

NCT04717765 2023-11-29

Photobiomodulation in Oral Lesions Resulting From Anti-neoplastic Prevention

60 enrolled

Head and Neck Neoplasms, Mouth Neoplasms, Osteoradionecrosis, Stomatitis, Xerostomia, Bisphosphonate-Associated Osteonecrosis of the Jaw

NCT03689712 2023-10-24

ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients

455 enrolled 11 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Stomatitis, Oral Ulcer

NCT05648682 2022-12-13

Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis

48 enrolled

Head and Neck Neoplasms, Stomatitis

NCT05055726 2022-11-16

BOOM

Phase 4 Completed

100 enrolled

Head and Neck Neoplasms, Stomatitis

NCT03237325 2022-11-08

DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck Cancer

266 enrolled 11 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Stomatitis

NCT04699487 2022-10-10

PrOMiSE

15 enrolled

Head and Neck Neoplasms, Stomatitis, Ulcer

NCT04529850 2022-08-16

Ph 2 Open Label Study of GC4419 to Reduce SOM Associated With Chemoradiotherapy for Head and Neck Cancer

38 enrolled 10 charts

Head and Neck Neoplasms, Stomatitis

NCT01668849 2022-08-09

Edible Plant Exosome Ability to Prevent Oral Mucositis Associated With Chemoradiation Treatment of Head and Neck Cancer

60 enrolled

Head and Neck Neoplasms, Stomatitis

NCT02531906 2022-07-25

Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation

60 enrolled

Squamous Cell Carcinoma of Head and Neck, Pain, Stomatitis

NCT04915599 2022-06-01

CooRay

10 enrolled

Head and Neck Neoplasms, Stomatitis

NCT02399228 2021-11-19

A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of Oral Mucositis

13 enrolled 10 charts

Head and Neck Neoplasms, Stomatitis

NCT05101889 2021-11-01

Benefits of Immunonutrition in Patients With Head and Neck Cancer Receiving Chemoradiation

110 enrolled

Head and Neck Neoplasms, Nasopharyngeal Neoplasms, Stomatitis

NCT02508389 2021-09-20

A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer

223 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck, Stomatitis

NCT00293462 2021-07-30

GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer

91 enrolled 16 charts

CNSHead & Neck

Head and Neck Neoplasms, Radiation Injuries, Stomatitis, Tongue Neoplasms, Esthesioneuroblastoma, Olfactory

NCT03988556 2021-04-30

SafePBM

72 enrolled

BreastHead & Neck

Breast Neoplasms, Head and Neck Neoplasms, Radiodermatitis, Stomatitis

NCT02608879 2020-08-28

OMDP

19 enrolled 17 charts

Mouth Neoplasms, Stomatitis

NCT01194466 2019-09-17

Transcutaneous Electrical Nerve Stimulation (TENS) and Head and Neck Cancer Pain (HNC) (TENS & HNC)

41 enrolled 6 charts

Head and Neck Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Pain, Stomatitis

NCT03416582 2019-09-13

Feasibility Study of a Nurse Intervention to Impact Mucositis Severity and Prevent Dehydration

11 enrolled

Head & NeckThoracic

Dehydration, Head and Neck Neoplasms, Lung Neoplasms, Stomatitis

NCT02324335 2019-01-16

Brilacidin

61 enrolled 12 charts

Head and Neck Neoplasms, Stomatitis, Mucositis

NCT01941992 2018-09-13

ROSAM

120 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Stomatitis

NCT01400620 2018-03-13

Safety and Efficacy of IZN-6N4 Oral Rinse for the Prevention of Oral Mucositis in Patients With Head and Neck Cancer

110 enrolled

Head and Neck Neoplasms, Stomatitis

NCT02630004 2018-03-01

MUCOMEL

Phase 1/2 Completed

84 enrolled

Head and Neck Neoplasms, Stomatitis, Mucositis

NCT00131638 2016-12-16

A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer

241 enrolled

Head and Neck Neoplasms, Neoplasms, Stomatitis

NCT00101582 2016-09-27

Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer

188 enrolled 19 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Stomatitis, Xerostomia, Oral Ulcer, Mucositis

NCT01921426 2016-09-22

A Phase 1 Dose Escalation Study of GC4419 in Combination With Chemoradiation for Squamous Cell Cancer of the Head & Neck

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Stomatitis

NCT00698204 2014-06-05

Cox-2 Inhibition in Radiation-induced Oral Mucositis

43 enrolled 10 charts

Head and Neck Neoplasms, Stomatitis, Mucositis

NCT01439724 2014-04-11

Low-level Laser Therapy to Prevent Oral Mucositis in Head and Neck Patients

94 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Stomatitis

NCT01283906 2013-09-12

MuGard

Phase 4 Completed

120 enrolled

Head and Neck Neoplasms, Stomatitis, Neoplasms, Squamous Cell, Mucositis

NCT00584597 2010-12-13

TRAUMEEL

14 enrolled

Head and Neck Neoplasms, Mouth Neoplasms, Stomatitis, Mucositis

NCT00790322 2010-02-19

Efficacy and Safety Study of SBG vs Placebo in Head and Neck Cancer Patients Undergoing Radiation Therapy

130 enrolled

Head and Neck Neoplasms, Neoplasms, Stomatitis

NCT00756951 2009-11-23

SCV-07 OM

59 enrolled

Head and Neck Neoplasms, Stomatitis

NCT00230191 2007-01-15

Safety and Efficacy of RK0202 in Oral Mucositis

110 enrolled