Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Active not recruiting 2

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gynecologic 9Thoracic 2Sarcoma 2Other solid neoplasm 2Head & Neck 2Genitourinary 2Gastrointestinal 2Dermatologic 2Breast 1

Conditions

Squamous Cell Carcinoma of Head and Neck 20Head and Neck Neoplasms 12Nasopharyngeal Carcinoma 10Sarcoma 3Uterine Cervical Neoplasms 2Thyroid Neoplasms 2Stomach Neoplasms 2Small Cell Lung Carcinoma 2Neoplasm Metastasis 2Nasopharyngeal Neoplasms 2Mesothelioma 2Melanoma 2Colorectal Neoplasms 2Carcinoma, Transitional Cell 2Carcinoma, Renal Cell 2Carcinoma, Non-Small-Cell Lung 2Uveal Melanoma 1Triple Negative Breast Neoplasms 1Thyroid Carcinoma, Anaplastic 1Testicular Germ Cell Tumor 1Recurrence 1Pancreatic Neoplasms 1Neuroendocrine Tumors 1Neoplasms, Unknown Primary 1Locally Advanced or Metastatic Solid Tumors for Phase 1, Dose Escalation and Phase 2 Safety Lead-in 1Laryngeal Neoplasms 1Hypopharyngeal Neoplasms 1Colonic Neoplasms 1Cholangiocarcinoma 1Carcinoma, Ovarian Epithelial 1

Interventions

pembrolizumab 30Nivolumab 10Cyclophosphamide 9fludarabine 7atezolizumab 7aldesleukin 5Paclitaxel 5Magnetic Resonance Spectroscopy 5Ipilimumab 5Carboplatin 5Biopsy 5cemiplimab 4Trastuzumab 4Interleukin-2 4Docetaxel 4Cisplatin 4spartalizumab 3durvalumab 3Specimen Handling 3Polymerase Chain Reaction 3Gene Expression Profiling 3Fulvestrant 3Fluorouracil 3tisotumab vedotin 2tislelizumab 2palbociclib 2fludarabine phosphate 2entinostat 2avelumab 2X-Rays 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Uterine Cervical Neoplasms × tislelizumab × Head & Neck × Clear all
NCT05238883 2025-11-21

A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

HiFiBiO Therapeutics

Phase 1 Active not recruiting
72 enrolled
DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Melanoma, Mesothelioma, Sarcoma, Stomach Neoplasms

NCT04802876 2025-03-21

ACROPOLI

SOLTI Breast Cancer Research Group

Phase 2 Active not recruiting
184 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Adenocarcinoma Of Esophagus, Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Uveal Melanoma, Anus Neoplasms, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasms, Unknown Primary, Sarcoma, Thyroid Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

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