Announcements Trials
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Phase

Phase 2 1Phase 1/2 1Phase 1 1

Status

Active not recruiting 2Recruiting 1

Sponsor Class

OTHER 1NIH 1INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Genitourinary 45Sarcoma 32Gastrointestinal 27CNS 27Lymphoid 14Myeloid 11Dermatologic 5Other solid neoplasm 3Head & Neck 3Endocrine 3Gynecologic 2

Conditions

Squamous Cell Carcinoma of Head and Neck 638Head and Neck Neoplasms 609Carcinoma, Non-Small-Cell Lung 202Thyroid Neoplasms 200Melanoma 145Nasopharyngeal Carcinoma 136Oropharyngeal Neoplasms 129Colorectal Neoplasms 129Mouth Neoplasms 128Neoplasms 113Breast Neoplasms 112Ovarian Neoplasms 105Lung Neoplasms 105Uterine Cervical Neoplasms 101Neoplasm Metastasis 93Carcinoma, Squamous Cell 86Stomach Neoplasms 84Carcinoma, Renal Cell 84Triple Negative Breast Neoplasms 79Pancreatic Neoplasms 72Esophageal Neoplasms 70Laryngeal Neoplasms 67Endometrial Neoplasms 67Urinary Bladder Neoplasms 61Sarcoma 58Prostatic Neoplasms 55Thyroid Cancer, Papillary 54Salivary Gland Neoplasms 49Carcinoma, Transitional Cell 47Carcinoma, Hepatocellular 46

Interventions

tipifarnib 1entrectinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Wilms Tumor × Head & Neck × 1 year × Clear all
NCT04284774 2026-05-27

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

National Cancer Institute (NCI)

Phase 2 Active not recruiting
5 enrolled 9 charts
CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Wilms Tumor, Neuroblastoma, Pheochromocytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Thyroid Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT07584499 2026-05-13

MRG003

Sun Yat-sen University

Phase 1 Recruiting
51 enrolled
CNSGenitourinaryHead & NeckSarcoma

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Rhabdoid Tumor

NCT02650401 2026-03-25

STARTRK-NG

Hoffmann-La Roche

Phase 1/2 Active not recruiting
69 enrolled 1 FDA
CNSEndocrineGenitourinaryHead & NeckSarcoma

Thyroid Cancer, Papillary, Brain Neoplasms, Glioma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Salivary Gland Neoplasms, Sarcoma, Sarcoma, Ewing, Central Nervous System Neoplasms, Nephroma, Mesoblastic

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