Clinical Trials

Head and Neck Neoplasms, Xerostomia

NCT02589938 2026-02-27

ACUPUNCTURE

258 enrolled 16 charts

Phase EARLY_PHASE1 Completed

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Radiation Injuries, Salivary Gland Neoplasms, Xerostomia

NCT05403125 2025-09-17

SDF Application in Oral Cancer Patients to Prevent Dental Caries

56 enrolled

Dental Caries, Pharyngeal Neoplasms, Xerostomia

NCT03552965 2025-09-02

Margin-Based Vs. Robust Photon Radiotherapy Planning in IMRT of HN-SQCC

23 enrolled 21 charts

Squamous Cell Carcinoma of Head and Neck, Xerostomia

NCT06122636 2025-04-03

HNC

62 enrolled

Dental Plaque, Head and Neck Neoplasms, Periodontal Diseases, Stomatitis, Xerostomia, Dysbiosis

NCT04608773 2024-02-01

Blinded Dry Mouth Spray Crossover Study

129 enrolled 12 charts

Head and Neck Neoplasms, Xerostomia

NCT04717765 2023-11-29

Photobiomodulation in Oral Lesions Resulting From Anti-neoplastic Prevention

60 enrolled

Head and Neck Neoplasms, Mouth Neoplasms, Osteoradionecrosis, Stomatitis, Xerostomia, Bisphosphonate-Associated Osteonecrosis of the Jaw

NCT05614843 2023-10-10

Photobiomodulation Therapy in Patients With Head and Neck Cancer Post-Radiotherapy

32 enrolled

Head and Neck Neoplasms, Neoplasms, Xerostomia

NCT02990468 2023-03-15

BMX-HN

Phase 1/2 Completed

29 enrolled 14 charts

Head and Neck Neoplasms, Xerostomia, Mucositis

NCT00595933 2022-09-07

Comparing Over-the-counter Dry Mouth Remedies After Radiation

Phase 1 Completed

28 enrolled

Head and Neck Neoplasms, Xerostomia

NCT02292368 2022-09-01

Neurological Effects of Acupuncture to Prevent Radiation-induced Xerostomia

30 enrolled

Head and Neck Neoplasms, Nasopharyngeal Neoplasms, Xerostomia

NCT02941276 2021-11-03

LEONIDAS-2

84 enrolled

Head and Neck Neoplasms, Xerostomia

NCT05025618 2021-09-05

ARTOME

132 enrolled

Oropharyngeal Neoplasms, Xerostomia

NCT01874587 2021-07-27

ARTIX

132 enrolled

Oropharyngeal Neoplasms, Xerostomia

NCT00430378 2021-06-10

Acupuncture for Prevention of Radiation-Induced Xerostomia

100 enrolled

Nasopharyngeal Neoplasms, Xerostomia

NCT04007081 2021-03-24

Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia

12 enrolled

Head and Neck Neoplasms, Xerostomia

NCT03151889 2020-08-12

TENS_HIR

67 enrolled

Head and Neck Neoplasms, Xerostomia

NCT04491435 2020-07-29

Saliva Substitute Mouthwash in NPC Survivors With Xerostomia: A Randomized Controlled Trial

94 enrolled

Nasopharyngeal Neoplasms, Xerostomia

NCT00001852 2019-12-17

Natural History of Salivary Gland Dysfunction and Sjogren's Syndrome

560 enrolled

Head & NeckLymphoid

Lymphoma, Salivary Gland Diseases, Sjogren's Syndrome, Xerostomia

NCT00656513 2019-11-19

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Phase 2/3 Completed

196 enrolled 13 charts

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms, Xerostomia

NCT03302676 2019-03-14

The Use of Chewing Gum for Xerostomia and Hyposalivation After Radiotherapy for Oral and Oropharyngeal Tumors

109 enrolled

Head and Neck Neoplasms, Xerostomia

NCT03035825 2019-02-08

Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients

73 enrolled

Head and Neck Neoplasms, Xerostomia

NCT00068237 2019-02-05

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

49 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Xerostomia

NCT01833650 2018-09-25

The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer

120 enrolled

Sialadenitis, Thyroid Neoplasms, Xerostomia

NCT00372320 2018-09-11

Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer

Phase 1 Completed

17 enrolled

Adenoviridae Infections, Head and Neck Neoplasms, Xerostomia

NCT02375451 2017-06-26

Effect of Childhood Radioiodine Therapy on Salivary Function

70 enrolled

Hyperthyroidism, Thyroid Neoplasms, Xerostomia

NCT00995319 2017-04-04

Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area

58 enrolled

Deglutition Disorders, Head and Neck Neoplasms, Xerostomia, Tooth Injuries, Malnutrition, Mucositis

NCT00095927 2017-01-04

Randomized Amifostine For SCCHN

58 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Xerostomia, Mucositis

NCT00101582 2016-09-27

Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer

188 enrolled 19 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Stomatitis, Xerostomia, Oral Ulcer, Mucositis

NCT02857413 2016-08-08

XEROSTOMIA

42 enrolled

Head and Neck Neoplasms, Xerostomia

NCT02854358 2016-08-03

Efficacy of Traditional Persian Medicine Preparation Versus Artificial Saliva for Radiation Induced Xerostomia

60 enrolled

Head and Neck Neoplasms, Xerostomia

NCT00375180 2016-02-25

Nutritional Status and Barriers to Dietary Intake in Head and Neck Cancer Patients

100 enrolled

Anosmia, Deglutition Disorders, Head and Neck Neoplasms, Xerostomia, Mucositis

NCT00168116 2016-02-24

Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure

42 enrolled

Head and Neck Neoplasms, Xerostomia

NCT02049112 2014-01-29

NIAGARA

Phase 4 Completed

210 enrolled

Head and Neck Neoplasms, Sjogren's Syndrome, Xerostomia

NCT01885065 2013-06-24

Efficacy of Novel Edible Gel-based Artificial Saliva in Cancer Patients

25 enrolled

Head and Neck Neoplasms, Neoplasms, Xerostomia

NCT00168181 2011-04-18

Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients

220 enrolled

Head and Neck Neoplasms, Neoplasms, Xerostomia

NCT00001167 2008-03-04

Ultrasound Evaluation of Tongue Movements in Speech and Swallowing

570 enrolled

Deglutition Disorders, Dysarthria, Otorhinolaryngologic Diseases, Otorhinolaryngologic Neoplasms, Pharyngeal Neoplasms, Speech, Speech Disorders, Xerostomia, Polymyositis

NCT00001523 2008-03-04

Structure and Functional Status of Parotid Glands Exposed to Therapeutic Irradiation

20 enrolled

Head and Neck Neoplasms, Radiation Injuries, Xerostomia

NCT00439478 2007-11-14

Dental Safety Profile of High-Dose Radioiodine Therapy

202 enrolled

Sialadenitis, Thyroid Neoplasms, Xerostomia

NCT00138827 2005-12-15

Mouth Care Regimes During Radiotherapy

Phase 4 Completed

50 enrolled

Head and Neck Neoplasms, Xerostomia, Mucositis

NCT00158691 2005-09-12

Intravenous Versus Subcutaneous Amifostine in Prevention of Xerostomia After RT for Head and Neck Carcinomas

296 enrolled