Clinical Trials Browser

OTHER × Head & Neck × 1 year × Clear all

NCT02713269 2026-04-17

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

Phase 2 Active not recruiting

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasms, Unknown Primary, Sarcoma, Spinal Cord Compression, Thyroid Neoplasms

NCT05119296 2026-04-17

Phase II Trial of Pembrolizumab in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

Phase 2 Active not recruiting

Thyroid Neoplasms

NCT05570851 2026-04-17

Alcohol Cessation Among Head and Neck Cancer Survivors

Phase NA Completed

Alcohol Drinking, Depression, Head and Neck Neoplasms, Social Isolation, Substance-Related Disorders

NCT06477692 2026-04-17

Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

Phase 2 Recruiting

Head and Neck Neoplasms

NCT06902623 2026-04-17

Lombardi197

Phase NA Recruiting

Oropharyngeal Neoplasms, Tonsillar Neoplasms

NCT06997068 2026-04-17

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Oral Cavity Cancer in a Rural Midwest United States Population

Phase 2 Recruiting

Mouth Neoplasms

NCT07445048 2026-04-17

Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma

Phase 3 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07535567 2026-04-17

NimoBenSeq

Phase 2/3 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck

NCT07536412 2026-04-17

Decision Aid Efficacy in Low Risk Thyroid Cancer

Phase NA Not yet recruiting

EndocrineHead & Neck

Papillary Thyroid Microcarcinoma, Thyroid Cancer, Papillary, Thyroid Neoplasms

NCT01266044 2026-04-16

Controlled Trial Of Acupuncture To Prevent Radiation-Induced Xerostomia

Phase 3 Active not recruiting

Head and Neck Neoplasms, Oropharyngeal Neoplasms, Xerostomia

NCT01627093 2026-04-16

Medical Data Collection of Patients With Head and Neck Cancer Treated With Proton Therapy

Active not recruiting

Head and Neck Carcinoma

NCT01709292 2026-04-16

Vemurafenib Neoadjuvant Trial in Locally Advanced Thyroid Cancer

Phase 2 Active not recruiting

EndocrineHead & Neck

Thyroid Cancer, Papillary, Thyroid Neoplasms

NCT02128906 2026-04-16

Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design

Phase 2 Recruiting

Carcinoma, Squamous Cell, Laryngeal Diseases

NCT02543320 2026-04-16

Neurofeedback in Decreasing Acute Radiotherapy-Induced Pain in Patients With Head and Neck Cancer

Phase NA Active not recruiting

Head and Neck Carcinoma

NCT02615275 2026-04-16

Bioelectrical Impedance Analysis in Estimating Body Composition in Patients With Stage I-IV Head and Neck Cancer Undergoing Radiation Therapy

Phase NA Active not recruiting

Head and Neck Carcinoma

NCT02662907 2026-04-16

Cough, Expiratory Training, and Chronic Aspiration After Head and Neck Radiotherapy

Phase NA Active not recruiting

Head and Neck Neoplasms

NCT03145077 2026-04-16

Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Diagnosing Osteoradionecrosis in Patients With Head and Neck Cancer That Is Primary, Has Come Back, or Has Spread to Other Places in the Body

Phase NA Recruiting

Head and Neck Neoplasms, Osteoradionecrosis

NCT03574792 2026-04-16

Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy

Phase 2 Completed

62 enrolled 10 charts

DermatologicHead & Neck

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8

NCT05743569 2026-04-16

3D Specimen Maps for RT Planning

Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06550050 2026-04-16

Clinical and Molecular Features of Oral Premalignancy and Oral Cancer

Mouth Neoplasms

NCT06702033 2026-04-16

MINT-2

Phase 2 Recruiting

Oropharyngeal Neoplasms

NCT07101432 2026-04-16

Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)

Phase 1 Recruiting

Head and Neck Neoplasms

NCT07361133 2026-04-16

Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT07470489 2026-04-16

Zanzalintinib Plus Cemiplimab for the Treatment of BRAF Wild-Type Anaplastic Thyroid Cancer

Phase 2 Not yet recruiting

EndocrineHead & Neck

Thyroid Carcinoma, Anaplastic

NCT07532538 2026-04-16

ML-HNC-Risk

Not yet recruiting

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms

NCT07532928 2026-04-16

A Bidirectional Study of Individualized Postoperative Adjuvant Treatment Decision Model for Locally Advanced Head and Neck Squamous Cell Carcinoma Based on Multimodal Dynamic Data

Enrolling by invitation

Squamous Cell Carcinoma of Head and Neck

NCT00076310 2026-04-15

OSI-774/Cisplatin/Taxotere in Head & Neck Squamous Cell Cancer

Phase 2 Active not recruiting

50 enrolled 11 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT02790853 2026-04-15

Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant Disorders

Phase EARLY_PHASE1 Active not recruiting

Mouth Diseases, Mouth Neoplasms

NCT03010150 2026-04-15

Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer

Nasopharyngeal Carcinoma, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms

NCT03114462 2026-04-15

Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer

Phase 1 Recruiting

Squamous Cell Carcinoma of Head and Neck

NCT03114501 2026-04-15

Dyadic Yoga Intervention for Patient With Head and Neck Cancer Undergoing Radiotherapy and Their Family Caregivers

Phase NA Active not recruiting

Head and Neck Neoplasms

NCT03624751 2026-04-15

Follow up for Patients With Thyroid Cancer Planed for Radioiodine Scan or Treatment

Active not recruiting

Thyroid Neoplasms

NCT03953352 2026-04-15

GIRAFE

Phase NA Withdrawn

Head and Neck Neoplasms

NCT04003051 2026-04-15

Web-Based Program in Helping Patients With Head and Neck Cancer Adhere to Swallowing Exercises and Coping Strategies

Phase 2 Recruiting

Head and Neck Neoplasms, Trismus

NCT04208490 2026-04-15

HN-STAR

Phase NA Active not recruiting

Head and Neck Neoplasms

NCT04693377 2026-04-15

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Phase NA Recruiting

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT04870762 2026-04-15

Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

Phase 2 Recruiting

Maxillary Sinus Neoplasms, Mouth Neoplasms, Parotid Neoplasms, Tongue Neoplasms, Tonsillar Neoplasms

NCT05036330 2026-04-15

ProvoxLife Adoption Trends for Heat-Moisture Exchanger

Active not recruiting

Head and Neck Neoplasms

NCT05039801 2026-04-15

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Phase 1 Recruiting

DermatologicGynecologicHead & NeckSarcoma

Squamous Cell Carcinoma of Head and Neck, Chondrosarcoma, Melanoma, Ovarian Neoplasms, Endometrial Neoplasms

NCT05187091 2026-04-15

SWOAR

Phase 3 Active not recruiting

Deglutition Disorders, Head and Neck Neoplasms

NCT06458036 2026-04-15

RAISE

Phase 2 Recruiting

Neoplasms, Thyroid Neoplasms

NCT06638931 2026-04-15

ANTARES

Phase 2 Recruiting

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT07172256 2026-04-15

CUE-101with Pembrolizumab for LA-HPV+HNSCCs

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck

NCT07213934 2026-04-15

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

Phase 1/2 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07455032 2026-04-15

Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas

Phase 1 Recruiting

Squamous Cell Carcinoma of Head and Neck

NCT07485569 2026-04-15

REPOTHYROID-II

Phase 1 Not yet recruiting

EndocrineHead & Neck

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT07524894 2026-04-15

SNIFF

Phase 2 Not yet recruiting

Head and Neck Neoplasms

NCT07531563 2026-04-15

C-Head-002

Phase NA Not yet recruiting

Head and Neck Neoplasms

NCT07532356 2026-04-15

Integrating Tumor Genomics and Urinary Exosomal Proteomics to Establish a Multi-Layer Biomarker Framework for Early Risk Stratification and Post-Treatment Surveillance in Fresh Thyroid Cancer Patients

Not yet recruiting

Thyroid Neoplasms

NCT03483337 2026-04-14

New MRI Biomarkers in Head and Neck Cancers

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence, Thyroid Neoplasms