Announcements Trials
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Phase

Phase 2 3Phase 1/2 1

Status

Recruiting 2Suspended 1Active not recruiting 1

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 7Head & Neck 4Gastrointestinal 4Thoracic 3Sarcoma 3Genitourinary 3Tumor-Agnostic 1Plasma cell 1Other solid neoplasm 1Lymphoid 1Breast 1

Conditions

Squamous Cell Carcinoma of Head and Neck 3Recurrent Head and Neck Carcinoma 1Head and Neck Neoplasms 1

Interventions

Cisplatin 85pembrolizumab 76Magnetic Resonance Spectroscopy 46Radiotherapy, Intensity-Modulated 41Specimen Handling 36Cetuximab 36Carboplatin 35Radiotherapy 34Nivolumab 28Paclitaxel 24Radiation 22Platinum 22Docetaxel 20Biopsy 201,2-diaminocyclohexaneplatinum II citrate 20Gemcitabine 19Surveys and Questionnaires 15Fluorouracil 14toripalimab 13Standard of Care 12Taxes 11cemiplimab 9atezolizumab 9Ipilimumab 9Drug Therapy 9Cyclophosphamide 9X-Rays 8Surgical Procedures, Operative 8Radiosurgery 7Immunoglobulin G 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Proton Therapy × Head & Neck × 90 days × Clear all
NCT04671667 2026-06-05

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

National Cancer Institute (NCI)

Phase 2 Recruiting
188 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT07213934 2026-04-15

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

University of Cincinnati

Phase 1/2 Recruiting
40 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03323463 2026-04-13

Major De-escalation to 30 Gy for Select Human Papillomavirus Associated Oropharyngeal Carcinoma

Memorial Sloan Kettering Cancer Center

Phase 2 Active not recruiting
316 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03164460 2026-03-20

Stereotactic Body Radiation Therapy or Intensity Modulated Radiation/Proton Therapy in Treating Patients With Recurrent Head and Neck Cancer

M.D. Anderson Cancer Center

Phase 2 Suspended
68 enrolled
Head & Neck

Recurrent Head and Neck Carcinoma

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