Clinical Trials

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT03358472 2025-12-03

Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)

89 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04854499 2025-11-19

ELEVATE HNSCC

193 enrolled 27 charts

Squamous Cell Carcinoma of Head and Neck

NCT00665392 2025-08-01

ECHO-07

42 enrolled 24 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT02358031 2025-07-18

MK-3475-048

882 enrolled 50 charts 2 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Head and Neck Neoplasms

NCT03944915 2025-05-11

DEPEND

35 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT03107182 2025-05-06

OPTIMA-II

72 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck

NCT00544414 2025-02-19

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

31 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04649476 2025-01-10

NEOPBOSCC

68 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck

NCT04428333 2024-10-09

INDUCE-4

Phase 3 Terminated

117 enrolled 33 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02258659 2024-09-24

OPTIMA

62 enrolled 13 charts

GastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections

NCT01047007 2023-09-21

A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005

Phase 1 Terminated

11 enrolled 10 charts

Esophageal Neoplasms, Head and Neck Neoplasms, Stomach Neoplasms

NCT02741570 2023-09-21

CheckMate 651

947 enrolled 19 charts

Head and Neck Neoplasms

NCT01711541 2023-06-07

Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer

Phase 1/2 Completed

24 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck, Oropharyngeal Neoplasms

NCT00274937 2022-10-25

Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer

111 enrolled 11 charts

Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7

NCT02383966 2022-05-13

CHANGE2

243 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck

NCT02052960 2021-11-02

RESGEX

240 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck

NCT00592501 2021-10-26

Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma

25 enrolled 16 charts

Nasopharyngeal Carcinoma

NCT02551159 2021-10-13

KESTREL

823 enrolled 23 charts

Squamous Cell Carcinoma of Head and Neck

NCT01566435 2020-10-01

Induction Chemotherapy With ACF Followed by Chemoradiation Therapy for Adv. Head & Neck Cancer

30 enrolled 21 charts

Head and Neck Neoplasms

NCT00736944 2020-09-09

Trial of 2 Cycles of Induction Chemo With Abraxane, Cetuximab, Cisplatin, & 5-FU for Advanced Head and Neck Cancer

30 enrolled 26 charts

Squamous Cell Carcinoma of Head and Neck

NCT00608205 2020-08-06

Radiation Therapy Cisplatin With or Without Fluorouracil Patients With Stage III or Stage IV Head and Neck Cancer

69 enrolled 47 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00721513 2020-04-07

Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

20 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01836029 2019-10-29

Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

195 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck

NCT00468169 2019-10-09

EPIC

110 enrolled 14 charts

Carcinoma, Head and Neck Neoplasms, Neoplasms

NCT01063075 2019-09-26

A Study in Advanced Solid Tumors

34 enrolled 15 charts

Head & NeckSarcoma

Carcinoma, Head and Neck Neoplasms, Sarcoma

NCT01099358 2019-09-26

Study in Advanced Solid Tumors

47 enrolled 15 charts

Head & NeckSarcoma

Carcinoma, Head and Neck Neoplasms, Sarcoma

NCT01081041 2019-09-25

A Study in Head and Neck Cancer

187 enrolled 19 charts

Head and Neck Neoplasms

NCT00756444 2018-11-15

A Randomized Phase 2 Pharmacokinetic Trial of Chemotherapy With or Without Panitumumab in Patients With Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck

67 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Recurrence

NCT00117572 2018-04-09

DeCIDE

285 enrolled 22 charts

Laryngeal Neoplasms, Paranasal Sinus Neoplasms, Pharyngeal Neoplasms

NCT00462735 2018-03-13

Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer

33 enrolled 15 charts

Head and Neck Neoplasms, Laryngeal Neoplasms, Nose Neoplasms, Paranasal Sinus Neoplasms, Pharyngeal Neoplasms

NCT00408694 2018-01-30

Bevacizumab, Cisplatin, Radiation Therapy, and Fluorouracil in Treating Patients With Stage IIB, Stage III, Stage IVA, or Stage IVB Nasopharyngeal Cancer

46 enrolled 10 charts

Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7

NCT00052429 2018-01-09

High-Dose Radiation Therapy Plus Chemotherapy in Treating Patients With Advanced Nose or Throat Cancer

Phase 1/2 Completed

25 enrolled 7 charts

Head and Neck Neoplasms

NCT00352118 2017-12-28

Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

4 enrolled 4 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Xerostomia, Mucositis

NCT01221753 2017-12-06

Docetaxel/Cisplatin/5-Fluorouracil (TPF) Human Papillomavirus (HPV) Squamous Cell Carcinoma Study

7 enrolled 6 charts

Squamous Cell Carcinoma of Head and Neck

NCT00400205 2017-11-06

Study of Induction Docetaxel, Cisplatin and 5-Fluorouracil

14 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Mouth Neoplasms

NCT00057785 2017-02-17

Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer

68 enrolled 5 charts

Head and Neck Neoplasms, Radiation Injuries

NCT00580983 2016-09-07

Optimized Intensity Modulated Irradiation for Head and Neck Cancer

Phase NA Completed

90 enrolled 11 charts

Head and Neck Neoplasms

NCT00599131 2015-12-03

Cetuximab and Radiation Therapy in Laryngeal Cancer Patients Who Have Responded to One Cycle of Chemotherapy (SPORE)

4 enrolled 5 charts

Laryngeal Neoplasms

NCT00565448 2015-07-30

Docetaxel in Combination With Cisplatin-5-fluorouracil for the Induction Treatment of Nasopharyngeal Carcinoma in Children and Adolescents

75 enrolled 10 charts

Nasopharyngeal Carcinoma, Carcinoma, Nasopharyngeal Neoplasms

NCT01177956 2014-09-03

CHANGE

73 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck

NCT00122460 2014-07-23

Cetuximab (Erbitux) in Combination With Cisplatin or Carboplatin and 5-Fluorouracil in the First Line Treatment of Subjects With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (EXTREME)

442 enrolled 18 charts

Head and Neck Neoplasms

NCT00971932 2014-04-08

Study of Cetuximab in Combination With Chemotherapy in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

33 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck

NCT00095875 2013-11-19

Combination Chemotherapy and Radiation in Treating Patients With Stage III or IV Head and Neck Cancer (Paradigm Trial)

145 enrolled 10 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00113399 2013-07-02

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery

Phase 3 Terminated

15 enrolled 5 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00392704 2013-02-22

Treatment of Head & Neck Cancer With Chemotherapy and Radiation

60 enrolled 6 charts

Head and Neck Neoplasms

NCT00352105 2012-11-05

Cisplatin, Fluorouracil, Iressa, and Radiation Therapy Patients With Locally Advanced Head and Neck Cancer

Phase 1/2 Completed

60 enrolled 12 charts