Clinical Trials Browser

Completed × Afatinib × Head & Neck × Clear all

NCT01783587 2026-03-25

Safety Study of Afatinib and Postoperative Radiation Therapy to Treat Head and Neck Cancer

Phase 1 Completed

Squamous Cell Carcinoma of Head and Neck

NCT02979977 2026-02-04

Dual Inhibition of EGFR With Afatinib and Cetuximab in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck

Phase 2 Completed

50 enrolled 14 charts

Squamous Cell Cancers of the Head and Neck

NCT01856478 2026-01-12

LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy

Phase 3 Completed

340 enrolled 23 charts

Head and Neck Neoplasms

NCT06494189 2025-12-29

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

Phase 1 Completed

Head and Neck Neoplasms

NCT05517330 2025-07-31

neoCHANCE-1

Phase 2 Completed

Head and Neck Neoplasms

NCT05516589 2025-05-22

neoCHANCE-2

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03695510 2022-04-21

ALPHA

Phase 2 Completed

Head and Neck Neoplasms

NCT01415674 2022-02-02

PREDICTOR

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck

NCT01427478 2021-06-01

BIBW2992ORL

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck

NCT01538381 2018-07-09

Neoadjuvant Afatinib Window Study in Squamous Cell Carcinoma of the Head and Neck

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck

NCT01345682 2018-02-15

LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy

Phase 3 Completed

483 enrolled 21 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02216617 2017-10-27

TAPIS

Phase 1 Completed

Squamous Cell Carcinoma of Head and Neck

NCT01721525 2017-10-25

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

Phase 1 Completed

Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT00514943 2016-07-26

BIBW 2992 (Afatinib) in Head & Neck Cancer

Phase 2 Completed

124 enrolled 31 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms