Clinical Trials

86 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT04862650 2026-02-10

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

46 enrolled

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT07400094 2026-02-10

NeoCamre-HN

50 enrolled

Squamous Cell Carcinoma of Head and Neck, Laryngeal Neoplasms, Mouth Neoplasms

NCT07290621 2026-02-06

Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat Cancer

30 enrolled

Oropharyngeal Neoplasms

NCT07371611 2026-01-28

Sintilimab Plus Chemotherapy as Neoadjuvant and Adjuvant Treatment for Locally Advanced Oral Squamous Cell Carcinoma

Phase 3 Recruiting

104 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT03829722 2026-01-22

Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer

26 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck

NCT07353723 2026-01-20

Nimotuzumab Combined With Toripalimab and Chemotherapy for Locally Advanced Tonsillar Cancer

10 enrolled

Pathologic Complete Response, Head and Neck Neoplasms

NCT02270814 2025-12-30

CACTUX

74 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00494182 2025-12-17

Sorafenib in Combination With Carboplatin and Paclitaxel in Treating Participants With Metastatic or Recurrent Head and Neck Squamous Cell Cancer

48 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT01154920 2025-12-17

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

128 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07267286 2025-12-05

Tirellizumab Combined With TP Neoadjuvant Therapy in the Treatment of Early Oral Squamous Cell Carcinoma （HNC-SYSU-005）

60 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT04643379 2025-10-22

Olaparib in Combination With Pembrolizumab and Carboplatin as First-Line Treatment of Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma

30 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck

NCT04954599 2025-10-07

Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI

Phase 1/2 Recruiting

126 enrolled

Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Triple Negative Breast Neoplasms

NCT07121595 2025-08-13

Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial

50 enrolled

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms

NCT05156970 2025-07-31

Camrelizumab in Combination With Chemotherapy or Apatinib Mesylate as First-Line Treatment for R/M HNSCC

81 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT04900623 2025-07-30

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

145 enrolled

Oropharyngeal Neoplasms

NCT06940180 2025-06-26

Toripalimab With Chemotherapy for Sinus Cancer

20 enrolled

Sinonasal undifferentiated carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Paranasal Sinus Neoplasms

NCT05726370 2025-06-22

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

28 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05388773 2025-06-19

Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

150 enrolled

Carcinoma, Squamous Cell, DNA Virus Infections, Head and Neck Neoplasms, Stomatognathic Diseases, Neoplasms, Glandular and Epithelial, Oropharyngeal Neoplasms, Otorhinolaryngologic Diseases, Otorhinolaryngologic Neoplasms, Papilloma, Pharyngeal Diseases, Pharyngeal Neoplasms, Tumor Virus Infections, Papillomavirus Infections

NCT05010629 2025-05-31

9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma

35 enrolled

Carcinoma, Adenoid Cystic, Neoplasm Metastasis, Salivary Gland Neoplasms

NCT03416153 2025-05-22

Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer

91 enrolled 11 charts

Oropharyngeal Neoplasms

NCT06234748 2025-05-13

ARTHOUSE

19 enrolled

Oropharyngeal Neoplasms

NCT03944915 2025-05-11

DEPEND

35 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT03107182 2025-05-06

OPTIMA-II

72 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck

NCT03342911 2025-04-24

Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery

34 enrolled 10 charts

Phase 3 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck

NCT06647563 2024-10-18

Neoadjuvant Toripalimab + Chemotherapy ± Cetuximab in Locally Advanced Head and Neck Squamous Cell Carcinoma (Neo-ICT)

355 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck

NCT05286619 2024-10-15

PIPER

63 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT02258659 2024-09-24

OPTIMA

62 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections

NCT04718415 2024-09-19

OOC-001

51 enrolled