Clinical Trials Browser

NETWORK × Cisplatin × Head & Neck × Clear all

NCT01898494 2026-04-01

Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Phase 2 Active not recruiting

519 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck, Oropharyngeal Neoplasms, Papillomavirus Infections

NCT03410615 2026-03-24

Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck

NCT02734537 2026-03-23

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Phase 2 Recruiting

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms

NCT05721755 2026-03-05

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Phase 3 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00003809 2026-02-27

Cisplatin With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03822897 2026-02-17

EVADER

Phase 2 Active not recruiting

103 enrolled 11 charts

Oropharyngeal Neoplasms

NCT01302834 2026-01-12

Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer

Phase 3 Completed

987 enrolled 59 charts

Head & NeckOther neoplasm

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Precancerous Conditions, Papillomavirus Infections

NCT01220583 2025-02-13

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

Phase 2 Active not recruiting

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT01969578 2024-11-05

Androgen Deprivation Therapy in Advanced Salivary Gland Cancer

Phase 2 Completed

Adenocarcinoma, Salivary Gland Neoplasms, Bulbo-Spinal Atrophy, X-Linked

NCT06084845 2024-07-25

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer

Phase 2 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms

NCT00502463 2024-02-07

ASOG-HNO1

Phase NA Completed

Head and Neck Neoplasms

NCT01711658 2023-10-17

TRYHARD

Phase 2 Completed

142 enrolled 22 charts

Head and Neck Neoplasms

NCT00820248 2023-08-22

Radiation + Cisplatin or Panitumumab in Locally Advanced Stage III or Stage IV Head and Neck Cancer

Phase 3 Completed

320 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00079079 2023-08-04

Cisplatin or Carboplatin Combined With Gemcitabine in Locally Advanced, Recurrent, or Metastatic Malignant Salivary Gland Tumor

Phase 2 Completed

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00047008 2023-07-07

Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With Head and Neck Cancer

Phase 3 Completed

743 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00096174 2023-06-29

Phase II Study of Concurrent C225, Cisplatin and Radiation in Stage IV Squamous Cell Carcinoma of the Head and Neck

Phase 2 Completed

69 enrolled 7 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01084083 2023-06-28

Induction Chemotherapy Followed By Cetuximab and Radiation in HPV-Associated Resectable Stage III/IV Oropharynx Cancer

Phase 2 Completed

90 enrolled 7 charts

Head & NeckOther neoplasm

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Precancerous Conditions, Tongue Neoplasms, Papillomavirus Infections

NCT00274937 2022-10-25

Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer

Phase 3 Completed

111 enrolled 11 charts

Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7

NCT00265941 2022-06-14

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Phase 3 Completed

940 enrolled 19 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01880359 2022-05-10

AF CRT +/- Nimorazole in HNSCC

Phase 3 Unknown

Locally Advanced Head and Neck HPV Negative Squamous Cell Cancers

NCT03673735 2021-05-10

ADHERE

Phase 3 Withdrawn

Squamous Cell Carcinoma of Head and Neck

NCT00004917 2020-10-22

Radiation Therapy With or Without Epoetin Alfa in Treating Anemic Patients With Head and Neck Cancer

Phase 3 Completed

Classical hematologyHead & Neck

Squamous Cell Carcinoma of Head and Neck, Anemia, Head and Neck Neoplasms

NCT00005088 2020-10-22

Radiation Therapy and Cisplatin in Treating Patients With Advanced Head and Neck Cancer

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03981068 2020-09-25

DAHANCA 37. Re-irradiation With Proton Radiotherapy

Phase NA Unknown

Head and Neck Neoplasms, Recurrence

NCT00006036 2020-04-06

Liposomal Lurtotecan Plus Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors

Phase 1 Completed

CNSGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Nasopharyngeal Neoplasms, Ovarian Neoplasms, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT00084318 2018-12-12

Adjuvant Cetuximab and Chemoradiotherapy Using Either Cisplatin or Docetaxel in Treating Patients With Resected Stage III or Stage IV Squamous Cell Carcinoma or Lymphoepithelioma of the Head and Neck

Phase 2 Completed

238 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00002839 2018-07-09

Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00003888 2018-07-09

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00498953 2018-07-09

Combination Chemotherapy and Radiation Therapy With or Without Lapatinib in Treating Patients With Locally Advanced Cancer of the Larynx or Hypopharynx

Phase 1/2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00646659 2018-07-09

Cetuximab, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Head and Neck Cancer That Cannot Be Removed By Surgery

Phase 2 Terminated

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00360971 2017-12-26

Palifermin in Lessening Oral Mucositis in Patients Undergoing Radiation Therapy and Chemotherapy for Locally Advanced Head and Neck Cancer

Phase 3 Terminated

21 enrolled 10 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Pain, Radiation Injuries, Mucositis

NCT01733823 2017-07-28

DAHANCA 28A: Phase I/II Study on Accelerated, Hyperfractionated Radiotherapy With Concomitant Cisplatin and Nimorazole

Phase 1/2 Completed

Squamous Cell Carcinoma of Head and Neck, Laryngeal Diseases

NCT01466257 2017-05-19

Biomarkers in Patients With Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01466244 2017-05-17

Biomarkers in Patients With Metastatic or Recurrent Head and Neck Cancer Treated With Cisplatin and Cetuximab on ECOG-E5397

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00057785 2017-02-17

Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer

Phase 2 Completed

68 enrolled 5 charts

Head and Neck Neoplasms, Radiation Injuries

NCT00005087 2015-11-17

Paclitaxel, Cisplatin, and Filgrastim Combined With Radiation Therapy in Treating Patients With Locally Recurrent Head and Neck Cancer

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00011999 2015-11-17

Chemotherapy and Radiation Therapy Following Surgery in Treating Patients With Head and Neck Cancer

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00720083 2015-11-17

Chemotherapy and Radiation Therapy (RT) With or Without Vandetanib in Treating Patients With High-Risk Stage III or Stage IV Head and Neck Cancer

Phase 2 Terminated

34 enrolled 5 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00002735 2015-09-30

SWOG-9451, Combination Chemo & RT For Patients With Stage III/Stage IV Cancer of the Hypopharynx or Tongue

Phase 2 Terminated

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00002999 2015-05-27

S9715, Chemotherapy and Radiation Therapy in Treating Patients With Advanced Cancer of the Nasopharynx

Phase 2 Withdrawn

Head and Neck Neoplasms, Nasopharyngeal Neoplasms

NCT01953952 2015-03-20

Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage III-IV Oropharyngeal Cancer

Phase 2 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Tongue Neoplasms

NCT00002932 2014-11-21

Cisplatin and Radiation Therapy in Treating Patients With Stage IV Cancer of the Head and Neck

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00002496 2014-01-24

Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Cancer of the Larynx

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00002670 2014-01-24

Radiation Therapy With or Without Chemotherapy in Treating Patients With Head and Neck Cancer That Has Been Removed During Surgery

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00113399 2013-07-02

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery

Phase 3 Terminated

15 enrolled 5 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00006248 2013-04-10

S0007 - Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00268372 2012-10-04

S0427, Combination Chemotherapy & RT in Treating Patients With Stage III or Stage IV Cancer of the Oropharynx

Phase 3 Terminated

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00025298 2012-09-24

Chemotherapy Plus Radiation Therapy With or Without Amifostine in Treating Patients With Locally Advanced Cancer of the Nasopharynx

Phase 2 Terminated

Head and Neck Neoplasms, Nasopharyngeal Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00002555 2012-07-02

High-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With Head and Neck Cancer

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00017173 2012-06-14

S0011, Gene Therapy & Surgery Followed by Chemo & RT in Newly Diagnosed Cancer of the Mouth or Throat

Phase 2 Terminated

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms