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Phase

Phase EARLY_PHASE1 1Phase 2/3 1Phase 2 1Phase 1 1

Status

Terminated 5Active not recruiting 5Completed 4Recruiting 3Withdrawn 1

Sponsor Class

OTHER 2NIH 2

Study Type

Interventional 4

Sponsor

Cancer Type

Gynecologic 20Gastrointestinal 14Genitourinary 8CNS 8Sarcoma 7Dermatologic 7Breast 7Thoracic 5Head & Neck 4Other solid neoplasm 2Lymphoid 1

Conditions

Squamous Cell Carcinoma of Head and Neck 3Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 1Oropharyngeal Neoplasms 1Mouth Neoplasms 1Laryngeal Neoplasms 1Hypopharyngeal Neoplasms 1Carcinoma 1

Interventions

Cisplatin 263Radiotherapy 166Cetuximab 159Docetaxel 105Fluorouracil 104pembrolizumab 94Radiotherapy, Intensity-Modulated 83Carboplatin 80Paclitaxel 73Nivolumab 59Erlotinib Hydrochloride 35Surveys and Questionnaires 32Gemcitabine 32durvalumab 30Radiation 29Drug Therapy 25Immunohistochemistry 21Gefitinib 21Capecitabine 21tremelimumab 18Bevacizumab 18Surgical Procedures, Operative 17Sorafenib 17Magnetic Resonance Spectroscopy 17Ipilimumab 17Pemetrexed 16lenvatinib 15atezolizumab 15Radiosurgery 15Gene Expression Profiling 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Immunoglobulin G × Head & Neck × Clear all
NCT03258554 2026-06-02

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

National Cancer Institute (NCI)

Phase 2/3 Completed
196 enrolled 31 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT03618654 2025-05-15

Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

Thomas Jefferson University

Phase EARLY_PHASE1 Completed
38 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03144778 2021-03-18

Durvalumab With or Without Tremelimumab in Treating Participants With Stage II-IVA Oropharyngeal Squamous Cell Cancer

M.D. Anderson Cancer Center

Phase 1 Completed
39 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT00408694 2018-01-30

Bevacizumab, Cisplatin, Radiation Therapy, and Fluorouracil in Treating Patients With Stage IIB, Stage III, Stage IVA, or Stage IVB Nasopharyngeal Cancer

National Cancer Institute (NCI)

Phase 2 Completed
46 enrolled 10 charts
Head & Neck

Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7

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