Clinical Trials Browser

Interventional × Neoadjuvant Therapy × Head & Neck × Clear all

NCT05544136 2026-02-27

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

Phase 2 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07353723 2026-01-20

Nimotuzumab Combined With Toripalimab and Chemotherapy for Locally Advanced Tonsillar Cancer

Phase 2 Recruiting

Pathologic Complete Response, Head and Neck Neoplasms

NCT02296684 2026-01-15

Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma

Phase 2 Completed

67 enrolled 15 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06235203 2025-06-03

Neoadjuvant vs Adjuvant in Locally Advanced Recurrent NPC

Phase 3 Recruiting

Nasopharyngeal Carcinoma

NCT06957938 2025-05-08

Comparing Neoadjuvant Chemotherapy Combined With PD-1 Inhibitor Versus Neoadjuvant Chemotherapy in Locally Advanced Laryngeal and Hypopharyngeal Carcinoma

Phase 3 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms

NCT00544414 2025-02-19

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

Phase 2 Completed

31 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05724329 2024-09-19

Neoadjuvant Tislelizumab in Combination With Dasatinib and Quercetin in Resectable HNSCC (COIS-01)

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck

NCT05582265 2024-05-17

Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Head and Neck Squamous Cell Carcinoma (REDUCTION-I)

Phase 3 Recruiting

Squamous Cell Carcinoma of Head and Neck

NCT05772208 2023-03-16

Intensified Treatments for Patients With Locally Advanced Nasopharyngeal Carcinoma With Detectable EBV DNA After One Cycle GP Regime Neoadjuvant Chemotherapy

Phase 3 Recruiting

Nasopharyngeal Carcinoma

NCT04929067 2023-02-17

Efficacy and Safety of Immunotherapy Combined With Neoadjuvant Chemotherapy in Patients With Locally Advanced HPV (-) Head and Neck Squamous Cell Carcinoma: a Phase II Clinical Trial

Phase 2 Unknown

Squamous Cell Carcinoma of Head and Neck

NCT05476965 2022-07-27

iCSDeR

Phase 2 Unknown

Squamous Cell Carcinoma of Head and Neck

NCT04849377 2022-07-07

RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC

Phase 2 Withdrawn

Squamous Cell Carcinoma of Head and Neck

NCT05351762 2022-07-05

Nimotuzumab Combined With Neoadjuvant Chemotherapy in the Treatment of Resectable LA HNSCC

Phase 2 Unknown

Squamous Cell Carcinoma of Head and Neck

NCT03366415 2022-03-04

Sequential or Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced NPC

Phase 3 Unknown

Nasopharyngeal Carcinoma

NCT03323424 2020-01-30

IRAM

Phase 2 Withdrawn

BreastGastrointestinalHead & Neck

Breast Neoplasms, Head and Neck Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT03923998 2019-04-23

Adjuvant ChemoRadiotherapy Prior to Surgery in Stage IVa Oral Cancers

Phase EARLY_PHASE1 Completed

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms

NCT00002839 2018-07-09

Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00498953 2018-07-09

Combination Chemotherapy and Radiation Therapy With or Without Lapatinib in Treating Patients With Locally Advanced Cancer of the Larynx or Hypopharynx

Phase 1/2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00601913 2018-07-05

Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery

Phase EARLY_PHASE1 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00705627 2014-05-28

A Multicenter Trial Comparing Multi-course Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma

Phase 3 Unknown

Nasopharyngeal Carcinoma

NCT00002702 2013-08-26

Surgery and Radiation Therapy With or Without Interleukin-2 in Treating Patients With Cancer of the Mouth or Oropharynx

Phase 3 Unknown

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT00276523 2012-10-31

PEG-interferon Alfa-2b in Treating Patients With Stage II, Stage III, or Stage IV Head and Neck Cancer That Can Be Removed By Surgery

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00357617 2010-12-24

Celecoxib in Treating Patients With Head and Neck Cancer That Can Be Removed By Surgery

Phase 1/2 Unknown

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms