Announcements Trials
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Phase

Phase 2 2Phase NA 1Phase 1/2 1Phase 1 1

Status

Completed 4Withdrawn 1

Sponsor Class

OTHER 5NIH 4NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Lymphoid 39Other hematologic neoplasm 33CNS 18Thoracic 17Breast 17Gastrointestinal 15Plasma cell 12Myeloid 9Genitourinary 9Dermatologic 9Sarcoma 6Gynecologic 6Head & Neck 5Other solid neoplasm 4Classical hematology 3Tumor-Agnostic 1Endocrine 1

Conditions

Squamous Cell Carcinoma of Head and Neck 4Carcinoma, Squamous Cell 2Vulvar Neoplasms 1Uterine Cervical Neoplasms 1Salivary Gland Neoplasms 1Penile Neoplasms 1Oropharyngeal Neoplasms 1Neoplasms, Squamous Cell 1Nasopharyngeal Neoplasms 1Nasopharyngeal Carcinoma 1Lung Neoplasms 1Head and Neck Neoplasms 1Esophageal Neoplasms 1Anus Neoplasms 1

Interventions

Cisplatin 416Radiotherapy 240Radiotherapy, Intensity-Modulated 178Cetuximab 177Docetaxel 166pembrolizumab 148Carboplatin 121Fluorouracil 113Paclitaxel 90Nivolumab 82Gemcitabine 82Radiation 72Surveys and Questionnaires 71Drug Therapy 70toripalimab 68Surgical Procedures, Operative 64Magnetic Resonance Spectroscopy 63Capecitabine 50Blood Specimen Collection 50Chemoradiotherapy 46Biopsy 44camrelizumab 41durvalumab 40Radiosurgery 40Standard of Care 38Erlotinib Hydrochloride 34nimotuzumab 32130-nm albumin-bound paclitaxel 32tislelizumab 31apatinib 30

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
OTHER × Vorinostat × Head & Neck × Clear all
NCT05608369 2025-04-04

HPV

Case Comprehensive Cancer Center

Phase 2 Withdrawn
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT04357873 2025-02-19

PEVOsq

UNICANCER

Phase 2 Completed
112 enrolled
GastrointestinalGenitourinaryGynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Penile Neoplasms, Vulvar Neoplasms, Neoplasms, Squamous Cell

NCT02538510 2024-11-26

Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery

University of Washington

Phase 1/2 Completed
50 enrolled 13 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Nasopharyngeal Neoplasms, Salivary Gland Neoplasms

NCT01064921 2019-06-04

Ph I Vorinostat in the Treatment of Advanced Staged Oropharyngeal Squamous Cell Carcinoma

Ohio State University Comprehensive Cancer Center

Phase 1 Completed
27 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Oropharyngeal Neoplasms

NCT00735826 2018-10-12

A Clinical Trial to Validate Molecular Targets of Vorinostat in Patients With Aerodigestive Tract Cancer

Dartmouth-Hitchcock Medical Center

Phase NA Completed
10 enrolled 7 charts
GastrointestinalHead & NeckThoracic

Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

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