Announcements Trials
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Phase

Phase 1 4Phase 2 2

Status

Completed 3Terminated 1

Sponsor Class

OTHER 3INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Other solid neoplasm 8Head & Neck 4Gynecologic 3Gastrointestinal 3CNS 3Thoracic 2Other hematologic neoplasm 2Tumor-Agnostic 1Sarcoma 1Myeloid 1Genitourinary 1Breast 1

Conditions

Squamous Cell Carcinoma of Head and Neck 3Stomach Neoplasms 1Laryngeal Neoplasms 1Head and Neck Neoplasms 1Esophageal Neoplasms 1

Interventions

pembrolizumab 84Cisplatin 73Cetuximab 54Radiotherapy 41Nivolumab 31Radiotherapy, Intensity-Modulated 26Docetaxel 26Fluorouracil 23Cyclophosphamide 23Paclitaxel 22fludarabine 19Radiation 18Gemcitabine 18Carboplatin 18Magnetic Resonance Spectroscopy 16Erlotinib Hydrochloride 16durvalumab 15atezolizumab 13fludarabine phosphate 10Radiosurgery 10Specimen Handling 9Interleukin-2 9Drug Therapy 9Biopsy 9130-nm albumin-bound paclitaxel 9budigalimab 8Ipilimumab 8Bortezomib 8tremelimumab 7toripalimab 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × adavosertib × Head & Neck × Clear all
NCT03028766 2024-09-19

WISTERIA

University of Birmingham

Phase 1 Completed
9 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Laryngeal Neoplasms

NCT01047007 2023-09-21

A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005

Merck Sharp & Dohme LLC

Phase 1 Terminated
11 enrolled 10 charts
GastrointestinalHead & Neck

Esophageal Neoplasms, Head and Neck Neoplasms, Stomach Neoplasms

NCT02585973 2021-06-29

Dose-escalating AZD1775 + Concurrent Radiation + Cisplatin for Intermediate/High Risk HNSCC

UNC Lineberger Comprehensive Cancer Center

Phase 1 Completed
12 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT02508246 2019-03-13

WEE1 Inhibitor MK-1775, Docetaxel, and Cisplatin Before Surgery in Treating Patients With Borderline Resectable Stage III-IVB Squamous Cell Carcinoma of the Head and Neck

University of Washington

Phase 1 Completed
12 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

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