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Phase

Phase 1 2Phase 1/2 1

Status

Completed 2Terminated 1

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Lymphoid 3

Conditions

Lymphoma 666Lymphoma, Non-Hodgkin 593Leukemia, Lymphocytic, Chronic, B-Cell 535Precursor Cell Lymphoblastic Leukemia-Lymphoma 485Lymphoma, Follicular 418Lymphoma, Large B-Cell, Diffuse 379Leukemia 358Hodgkin Disease 354Lymphoma, Mantle-Cell 306Leukemia, Myeloid, Acute 250Multiple Myeloma 237Myelodysplastic Syndromes 214Lymphoma, B-Cell, Marginal Zone 196Recurrence 195Burkitt Lymphoma 189Waldenstrom Macroglobulinemia 155Leukemia, Myelogenous, Chronic, BCR-ABL Positive 130Lymphoma, B-Cell 127Neoplasms 118Lymphoma, T-Cell, Cutaneous 116Lymphoma, Large-Cell, Anaplastic 113Hematologic Neoplasms 103Lymphoma, Large-Cell, Immunoblastic 100Mycosis Fungoides 95Myeloproliferative Disorders 94Sezary Syndrome 86Lymphoma, T-Cell, Peripheral 83Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 81Lymphoma, T-Cell 74Primary Myelofibrosis 70

Interventions

zanubrutinib 2tirabrutinib 1obinutuzumab 1idelalisib 1Voriconazole 1Fluconazole 1Diltiazem 1Clarithromycin 16-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo(1,2-a)pyrazin-8-amine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Has results × B-cell Malignancies × Lymphoid × Clear all
NCT02457598 2025-06-17

Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination With Other Targeted Anti-cancer Therapies in Adults With B-cell Malignancies

Gilead Sciences

Phase 1 Terminated
203 enrolled 43 charts
Lymphoid

B-cell Malignancies

NCT04551963 2024-10-26

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

BeiGene

Phase 1 Completed
26 enrolled 20 charts
Lymphoid

B-cell Malignancies

NCT02343120 2022-04-28

Study of the Safety and Pharmacokinetics of BGB-3111 in Subjects With B-Cell Lymphoid Malignancies

BeiGene

Phase 1/2 Completed
385 enrolled 29 charts 2 FDA
Lymphoid

B-cell Malignancies

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