Announcements Trials
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Phase

Phase 1 2

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 3Other hematologic neoplasm 2Lymphoid 2

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 171Lymphoma 93Leukemia 63Burkitt Lymphoma 57Lymphoma, Non-Hodgkin 50Lymphoma, Large B-Cell, Diffuse 44Lymphoma, Mantle-Cell 38Lymphoma, Follicular 30Recurrence 29Hodgkin Disease 29Waldenstrom Macroglobulinemia 27Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 27Leukemia, Lymphocytic, Chronic, B-Cell 26Multiple Myeloma 21Lymphoma, B-Cell, Marginal Zone 17Lymphoma, Extranodal NK-T-Cell 16Leukemia, Biphenotypic, Acute 16Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 13Lymphoma, B-Cell 13Leukemia, Myeloid, Acute 13Lymphoma, Large-Cell, Immunoblastic 11Lymphoma, T-Cell, Peripheral 10Neoplasms 9Lymphoma, Large-Cell, Anaplastic 9Lymphoma, T-Cell, Cutaneous 8Lymphoma, T-Cell 7Intraocular Lymphoma 6Hematologic Neoplasms 6Blast Crisis 6Sezary Syndrome 5

Interventions

fludarabine phosphate 6Cyclophosphamide 6Whole-Body Irradiation 4Mycophenolic Acid 4fludarabine 3Thiotepa 3Methotrexate 3Cyclosporine 3Tacrolimus 2Specimen Handling 2Peripheral Blood Stem Cell Transplantation 2Dexamethasone 2Cyclosporins 2Calcium Dobesilate 2tagraxofusp 1merphos 1lorvotuzumab mertansine 1dexamethasone acetate 1dexamethasone 21-phosphate 1auricularum 1X-Rays 1Vincristine 1Sirolimus 1Salvia hispanica seed extract 1Rituximab 1Ranitidine 1Nivolumab 1Mesna 1Magnetic Resonance Spectroscopy 1MK 2206 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Blastic Plasmacytoid Dendritic Cell Neoplasm × Dexamethasone × Lymphoid × Clear all
NCT04681105 2026-01-28

Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies

City of Hope Medical Center

Phase 1 Completed
13 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Hairy Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Hematologic Neoplasms, Mastocytosis, Systemic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05476770 2024-12-06

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Therapeutic Advances in Childhood Leukemia Consortium

Phase 1 Recruiting
54 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Hodgkin Disease, Leukemia, Biphenotypic, Acute, Lymphoma, B-Cell, Lymphoma, T-Cell, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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