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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Lymphoid 1Gynecologic 1Dermatologic 1Breast 1

Conditions

Lymphoma, Mantle-Cell 66Lymphoma 65Lymphoma, Non-Hodgkin 43Lymphoma, Follicular 42Precursor Cell Lymphoblastic Leukemia-Lymphoma 41Lymphoma, Large B-Cell, Diffuse 34Waldenstrom Macroglobulinemia 33Lymphoma, B-Cell, Marginal Zone 30Leukemia, Lymphocytic, Chronic, B-Cell 28Recurrence 18Multiple Myeloma 17Hodgkin Disease 17Lymphoma, B-Cell 14Leukemia, Myeloid, Acute 14Burkitt Lymphoma 14Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 13Lymphoma, Large-Cell, Anaplastic 13Leukemia 12Immunoblastic Lymphadenopathy 12Mycosis Fungoides 11Lymphoma, T-Cell, Cutaneous 11Lymphoma, Large-Cell, Immunoblastic 11Sezary Syndrome 10Lymphoma, T-Cell, Peripheral 10Neoplasms, Plasma Cell 9Neoplasms 9Lymphoma, T-Cell 8Myelodysplastic Syndromes 7Lymphoma, Extranodal NK-T-Cell 7Leukemia, Myelogenous, Chronic, BCR-ABL Positive 6

Interventions

Therapeutics 2Cyclophosphamide 2liposomal doxorubicin 1flt3 ligand protein 1entinostat 1Watchful Waiting 1Vorinostat 1Thrombopoietin 1Thiotepa 1Thalidomide 1Stem Cell Factor 1SUB1 protein, human 1Radiotherapy 1Psychiatric Rehabilitation 1Physical Therapy Modalities 1Peripheral Blood Stem Cell Transplantation 1Melphalan 1Filgrastim 1Fentanyl 1Etoposide 1Docetaxel 1Cryosurgery 1Carmustine 1Carboplatin 1Capecitabine 1Busulfan 1Bortezomib 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Breast Neoplasms, Male × Bortezomib × Lymphoid × Clear all
NCT00237627 2012-05-18

Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer

UNC Lineberger Comprehensive Cancer Center

Phase 1/2 Completed
107 enrolled
BreastDermatologicGynecologicLymphoidOther hematologic neoplasmPlasma cell

Congenital Abnormalities, Carcinoma, Ovarian Epithelial, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Ovarian Neoplasms, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Breast Neoplasms, Male, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Intraocular Lymphoma

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