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Phase

Phase 1 1

Status

Completed 18Terminated 4Unknown 2Withdrawn 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 5Sarcoma 4Other solid neoplasm 1Other hematologic neoplasm 1Lymphoid 1

Conditions

Lymphoma 128Leukemia, Lymphocytic, Chronic, B-Cell 96Precursor Cell Lymphoblastic Leukemia-Lymphoma 90Lymphoma, Non-Hodgkin 83Lymphoma, Follicular 76Lymphoma, Large B-Cell, Diffuse 71Leukemia 60Lymphoma, Mantle-Cell 51Burkitt Lymphoma 48Hodgkin Disease 44Leukemia, Myeloid, Acute 42Lymphoma, B-Cell, Marginal Zone 41Lymphoma, B-Cell 40Recurrence 38Lymphoma, T-Cell, Cutaneous 27Mycosis Fungoides 26Myelodysplastic Syndromes 25Waldenstrom Macroglobulinemia 24Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 24Multiple Myeloma 21Lymphoma, Large-Cell, Immunoblastic 21Lymphoma, Large-Cell, Anaplastic 21Sezary Syndrome 19Neoplasms 19Hematologic Neoplasms 18Myeloproliferative Disorders 17Lymphoma, Extranodal NK-T-Cell 16Leukemia, Myelomonocytic, Chronic 14Leukemia, Myelogenous, Chronic, BCR-ABL Positive 14Leukemia, Biphenotypic, Acute 14

Interventions

N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine 1Drug Therapy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Withdrawn × Choroid Plexus Neoplasms × Lymphoid × Clear all
NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Children's Oncology Group

Phase 1 Withdrawn
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

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