Announcements Trials
Browse Landscape

Phase

Phase 2 4

Status

Completed 4

Sponsor Class

OTHER 3INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Lymphoid 4Plasma cell 1Other hematologic neoplasm 1CNS 1

Conditions

Lymphoma 666Lymphoma, Non-Hodgkin 593Leukemia, Lymphocytic, Chronic, B-Cell 535Precursor Cell Lymphoblastic Leukemia-Lymphoma 485Lymphoma, Follicular 418Lymphoma, Large B-Cell, Diffuse 379Leukemia 358Hodgkin Disease 354Lymphoma, Mantle-Cell 306Leukemia, Myeloid, Acute 250Multiple Myeloma 237Myelodysplastic Syndromes 214Lymphoma, B-Cell, Marginal Zone 196Recurrence 195Burkitt Lymphoma 189Waldenstrom Macroglobulinemia 155Leukemia, Myelogenous, Chronic, BCR-ABL Positive 130Lymphoma, B-Cell 127Neoplasms 118Lymphoma, T-Cell, Cutaneous 116Lymphoma, Large-Cell, Anaplastic 113Hematologic Neoplasms 103Lymphoma, Large-Cell, Immunoblastic 100Mycosis Fungoides 95Myeloproliferative Disorders 94Sezary Syndrome 86Lymphoma, T-Cell, Peripheral 83Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 81Lymphoma, T-Cell 74Primary Myelofibrosis 70

Interventions

siltuximab 1axicabtagene ciloleucel 1Interleukin 1 Receptor Antagonist Protein 1Gelsolin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Has results × Cytokine Release Syndrome × Lymphoid × Clear all
NCT04975555 2026-06-03

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

University of Alabama at Birmingham

Phase 2 Completed
24 enrolled 8 charts
LymphoidOther hematologic neoplasmPlasma cell

Cytokine Release Syndrome, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04150913 2025-11-25

A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity

Massachusetts General Hospital

Phase 2 Completed
15 enrolled 17 charts
Lymphoid

Cytokine Release Syndrome, Lymphoma, Non-Hodgkin, Neurotoxicity Syndromes

NCT04466098 2025-01-29

Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19)

Masonic Cancer Center, University of Minnesota

Phase 2 Completed
8 enrolled 21 charts
Lymphoid

Cytokine Release Syndrome, COVID-19, Lymphoma, Follicular, Respiratory Distress Syndrome

NCT04358406 2023-11-28

Rhu-pGSN for Severe Covid-19 Pneumonia

BioAegis Therapeutics Inc.

Phase 2 Completed
64 enrolled 17 charts
Lymphoid

Cytokine Release Syndrome, COVID-19, Lymphoma, Follicular, Pneumonia

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