Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Active not recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 2Other hematologic neoplasm 1CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 147Leukemia, Lymphocytic, Chronic, B-Cell 140Lymphoma 116Lymphoma, Non-Hodgkin 112Leukemia, Myeloid, Acute 95Leukemia 92Myelodysplastic Syndromes 90Hodgkin Disease 68Lymphoma, B-Cell 61Leukemia, Myelogenous, Chronic, BCR-ABL Positive 53Multiple Myeloma 52Lymphoma, Mantle-Cell 52Lymphoma, Large B-Cell, Diffuse 50Lymphoma, Follicular 50Recurrence 43Burkitt Lymphoma 41Hematologic Neoplasms 36Myeloproliferative Disorders 31Lymphoma, B-Cell, Marginal Zone 30Neoplasms, Plasma Cell 20Primary Myelofibrosis 19Leukemia, Biphenotypic, Acute 18Anemia, Refractory, with Excess of Blasts 18Lymphoma, T-Cell 17Leukemia, Myelomonocytic, Chronic 15Graft vs Host Disease 15Anemia, Aplastic 15Leukemia, Prolymphocytic 14Neoplasms 12Leukemia, B-Cell 12

Interventions

siltuximab 2fludarabine phosphate 2fludarabine 2Interleukin 1 Receptor Antagonist Protein 2Cyclophosphamide 2AP 1903 reagent 2obinutuzumab 1glofitamab 1axicabtagene ciloleucel 1Oxaliplatin 1Neuropsychological Tests 1Magnetic Resonance Spectroscopy 1Gemcitabine 1Gelsolin 1Contrast Media 1Bendamustine Hydrochloride 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Cytokine Release Syndrome × fludarabine × Lymphoid × Clear all
NCT03696784 2025-12-08

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

UNC Lineberger Comprehensive Cancer Center

Phase 1 Active not recruiting
19 enrolled
Lymphoid

Cytokine Release Syndrome, Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, B-Cell, Neurotoxicity Syndromes

NCT03016377 2025-10-27

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

UNC Lineberger Comprehensive Cancer Center

Phase 1/2 Active not recruiting
17 enrolled
LymphoidOther hematologic neoplasm

Cytokine Release Syndrome, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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