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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 1Lymphoid 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 87Leukemia 31Lymphoma 21Burkitt Lymphoma 19Leukemia, Biphenotypic, Acute 11Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 8Lymphoma, Extranodal NK-T-Cell 8Recurrence 6Lymphoma, Non-Hodgkin 6Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 4Dendritic Cell Sarcoma, Interdigitating 4Neoplasm, Residual 3Leukemia, Myeloid, Acute 3Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large B-Cell, Diffuse 2Down Syndrome 2Thrombocytopenia 1Neutropenia 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell 1Lymphoma, Mantle-Cell 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma, B-Cell 1Lymphohistiocytosis, Hemophagocytic 1Leukemia, Prolymphocytic 1Leukemia, Lymphocytic, Chronic, B-Cell 1Hypersensitivity 1Hematologic Neoplasms 1Drug-Related Side Effects and Adverse Reactions 1

Interventions

Etoposide 4pegaspargase 3Cyclophosphamide 3Methylprednisolone 2Gemcitabine 2Flow Cytometry 2Dexamethasone 2Alemtuzumab 2zanubrutinib 1sintilimab 1ruxolitinib 1fludarabine phosphate 1fludarabine 1Whole-Body Irradiation 1Vincristine 1Thiotepa 1Th1-Th2 Balance 1Tacrolimus 1Rituximab 1Prednisone 1Polymerase Chain Reaction 1N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide 1Methylprednisolone Hemisuccinate 1Melphalan 1In Situ Hybridization 1Immunohistochemistry 1EPOCH protocol 1Doxorubicin 1Cytogenetic Analysis 1Cytarabine 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Lymphohistiocytosis, Hemophagocytic × Asparaginase × Lymphoid × Clear all
NCT07525466 2026-04-13

Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)

Beijing Tongren Hospital

Phase 1/2 Recruiting
25 enrolled
LymphoidMyeloid

Lymphohistiocytosis, Hemophagocytic, Lymphoma, Extranodal NK-T-Cell

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