Announcements Trials
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Phase

Phase 1/2 2

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 4Lymphoid 2Other hematologic neoplasm 1Classical hematology 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 54Lymphoma 49Leukemia 44Burkitt Lymphoma 39Lymphoma, Large B-Cell, Diffuse 37Lymphoma, Follicular 37Lymphoma, Non-Hodgkin 34Lymphoma, Large-Cell, Immunoblastic 27Leukemia, Myeloid, Chronic-Phase 27Leukemia, Lymphocytic, Chronic, B-Cell 27Myelodysplastic Syndromes 26Leukemia, Myeloid, Acute 25Leukemia, Myeloid, Accelerated Phase 25Hodgkin Disease 22Lymphoma, Mantle-Cell 21Lymphoma, B-Cell, Marginal Zone 21Dendritic Cell Sarcoma, Interdigitating 20Multiple Myeloma 19Recurrence 18Myeloproliferative Disorders 18Graft vs Host Disease 18Blast Crisis 18Neoplasms, Plasma Cell 17Leukemia, Myelomonocytic, Chronic 16Leukemia, Biphenotypic, Acute 16Congenital Abnormalities 14Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 13Lymphoma, T-Cell, Cutaneous 13Primary Myelofibrosis 12Lymphoma, Large-Cell, Anaplastic 12

Interventions

Etoposide 4pegaspargase 3Cyclophosphamide 3Methylprednisolone 2Gemcitabine 2Flow Cytometry 2Dexamethasone 2Alemtuzumab 2zanubrutinib 1sintilimab 1ruxolitinib 1fludarabine phosphate 1fludarabine 1Whole-Body Irradiation 1Vincristine 1Thiotepa 1Th1-Th2 Balance 1Tacrolimus 1Rituximab 1Prednisone 1Polymerase Chain Reaction 1N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide 1Methylprednisolone Hemisuccinate 1Melphalan 1In Situ Hybridization 1Immunohistochemistry 1EPOCH protocol 1Doxorubicin 1Cytogenetic Analysis 1Cytarabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Lymphohistiocytosis, Hemophagocytic × Methylprednisolone × Lymphoid × Clear all
NCT07525466 2026-04-13

Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)

Beijing Tongren Hospital

Phase 1/2 Recruiting
25 enrolled
LymphoidMyeloid

Lymphohistiocytosis, Hemophagocytic, Lymphoma, Extranodal NK-T-Cell

NCT02061800 2024-06-04

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Columbia University

Phase 1/2 Active not recruiting
14 enrolled
Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Neutropenia, Severe Congenital, Autosomal Recessive 3, Bone Marrow Failure Disorders, Shwachman-Diamond Syndrome, Primary Immunodeficiency Diseases, Acquired Immunodeficiency Syndrome, Anemia, Aplastic, Anemia, Sickle Cell, Hemoglobinopathies, Histiocytosis, Langerhans-Cell, Lymphoma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Histiocytosis, Anemia, Diamond-Blackfan, Lymphohistiocytosis, Hemophagocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Macrophage Activation Syndrome

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