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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Sarcoma 1Other solid neoplasm 1Other hematologic neoplasm 1Lymphoid 1

Conditions

Recurrence 5Lymphoma, Non-Hodgkin 5Lymphoma, Follicular 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Neoplasms 3Lymphoma, Large B-Cell, Diffuse 3Lymphoma 3Leukemia, Myeloid, Acute 3Leukemia, Lymphocytic, Chronic, B-Cell 3Wilms Tumor 2Testicular Neoplasms 2Sezary Syndrome 2Primary Myelofibrosis 2Neuroblastoma 2Mycosis Fungoides 2Multiple Myeloma 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, Myeloid, Chronic-Phase 2Leukemia, Myeloid, Accelerated Phase 2Leukemia, Hairy Cell 2Infections 2Hodgkin Disease 2Hematologic Neoplasms 2Dendritic Cell Sarcoma, Interdigitating 2Carcinoma, Ovarian Epithelial 2Burkitt Lymphoma 2Breast Neoplasms 2

Interventions

tazemetostat 2Pemetrexed 2Cisplatin 2ruxolitinib 1ribociclib 1belinostat 1avelumab 1abemaciclib 1Sirolimus 1Rifampin 1Quality of Life 1Patient Reported Outcome Measures 1Molecular Diagnostic Techniques 1Midazolam 1Letrozole 1LY3023414 1Itraconazole 1Immunotherapy, Adoptive 1Immunotherapy 1Imatinib Mesylate 1Fulvestrant 1Fluorodeoxyglucose F18 1Drug Therapy 1Doxepin 1Biological Therapy 14-(3-fluoropropyl)glutamic acid 1(4S)-4-(3-(18F)fluoropropyl)-L-glutamate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Mesothelioma × Itraconazole × Lymphoid × Clear all
NCT04537715 2025-02-19

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Ipsen

Phase 1 Completed
42 enrolled 39 charts
LymphoidOther hematologic neoplasmOther solid neoplasmSarcomaThoracic

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Hematologic Neoplasms

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