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Phase

Phase EARLY_PHASE1 1Phase 1 1

Status

Recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 3Myeloid 3Lymphoid 2Plasma cell 1Classical hematology 1

Conditions

Multiple Myeloma 7Lymphoma, Non-Hodgkin 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Recurrence 5Lymphoma 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Leukemia, Myeloid, Acute 4Leukemia, Lymphocytic, Chronic, B-Cell 3Hodgkin Disease 3Hematologic Neoplasms 3Waldenstrom Macroglobulinemia 2Plasmablastic Lymphoma 2Myelodysplastic Syndromes 2Lymphoma, Large B-Cell, Diffuse 2Primary Myelofibrosis 1Neoplasm, Residual 1Mycosis Fungoides 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, T-Cell 1Lymphoma, Mantle-Cell 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma, B-Cell 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Hypergammaglobulinemia 1Breast Neoplasms 1Anemia, Aplastic 1

Interventions

Cyclophosphamide 172fludarabine phosphate 132Tacrolimus 100Mycophenolic Acid 92fludarabine 90Busulfan 88Whole-Body Irradiation 83Peripheral Blood Stem Cell Transplantation 77Antilymphocyte Serum 71Melphalan 69Filgrastim 63Cyclosporine 62Methotrexate 54Radiotherapy 40Thiotepa 39Cord Blood Stem Cell Transplantation 35Granulocyte Colony-Stimulating Factor 34Stem Cell Transplantation 32thymoglobulin 29Sirolimus 27Methylprednisolone 26Rituximab 24Cytarabine 23Clofarabine 23Etoposide 22Alemtuzumab 20Azacitidine 17Specimen Handling 14Cyclosporins 13sargramostim 12

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Myelodysplastic Syndromes × daratumumab × Lymphoid × Clear all
NCT06287944 2026-05-18

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

City of Hope Medical Center

Phase 1 Recruiting
15 enrolled
LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06398457 2025-09-26

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase EARLY_PHASE1 Recruiting
8 enrolled
Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Anemia, Aplastic, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

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