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Phase

Phase EARLY_PHASE1 1Phase 2 1

Status

Withdrawn 1Completed 1

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 2CNS 1

Conditions

Lymphoma, Large B-Cell, Diffuse 416Lymphoma 406Lymphoma, Non-Hodgkin 344Leukemia, Lymphocytic, Chronic, B-Cell 313Lymphoma, Follicular 301Lymphoma, Mantle-Cell 226Lymphoma, B-Cell, Marginal Zone 161Lymphoma, B-Cell 112Leukemia 112Burkitt Lymphoma 110Waldenstrom Macroglobulinemia 99Precursor Cell Lymphoblastic Leukemia-Lymphoma 90Recurrence 82Hodgkin Disease 60Lymphoma, Large-Cell, Immunoblastic 57Neoplasms 33Lymphoma, Large-Cell, Anaplastic 26Myelodysplastic Syndromes 24Leukemia, Myeloid, Acute 24Multiple Myeloma 21Dendritic Cell Sarcoma, Interdigitating 19Intraocular Lymphoma 17Leukemia, Prolymphocytic 15Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 14Lymphoma, T-Cell 14Hematologic Neoplasms 13Lymphoproliferative Disorders 12Leukemia, Hairy Cell 11Leukemia, B-Cell 11Hematologic Diseases 11

Interventions

Vincristine 4Radiotherapy 3Procarbazine 3Methotrexate 3Cytarabine 3Rituximab 2Prednisolone 2Cyclophosphamide 2motexafin gadolinium 1glutamic acid diethyl ester 1glucarpidase 1fludarabine phosphate 1fludarabine 1axicabtagene ciloleucel 1Simvastatin 1Neuropsychological Tests 1Methylprednisolone 1Magnetic Resonance Spectroscopy 1Leucovorin 1Interleukin 1 Receptor Antagonist Protein 1Glutamine 1Glutamic Acid 1Etoposide 1Doxorubicin 1Dietary Supplements 1Dexamethasone 1Contrast Media 1Bendamustine Hydrochloride 1Baclofen 1AP 1903 reagent 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neurotoxicity Syndromes × Rituximab × Lymphoid × Clear all
NCT01399372 2023-07-20

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Radiation Therapy Oncology Group

Phase 2 Completed
91 enrolled 17 charts
Lymphoid

Lymphoma, Radiation Injuries, Neurotoxicity Syndromes

NCT00734773 2012-05-18

Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL

Northwestern University

Phase EARLY_PHASE1 Withdrawn
CNSLymphoid

Lymphoma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

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