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Phase

Phase 2 2Phase EARLY_PHASE1 1Phase 1 1

Status

Completed 3Withdrawn 1

Sponsor Class

OTHER 2NIH 1NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

Lymphoid 4Other hematologic neoplasm 1CNS 1

Conditions

Lymphoma 217Precursor Cell Lymphoblastic Leukemia-Lymphoma 192Lymphoma, Large B-Cell, Diffuse 173Burkitt Lymphoma 91Lymphoma, Non-Hodgkin 90Leukemia 80Lymphoma, Follicular 79Lymphoma, Mantle-Cell 53Hodgkin Disease 46Lymphoma, B-Cell 31Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 30Lymphoma, Large-Cell, Anaplastic 29Lymphoma, T-Cell, Peripheral 28Lymphoma, Large-Cell, Immunoblastic 27Recurrence 24Lymphoma, B-Cell, Marginal Zone 22Leukemia, Lymphocytic, Chronic, B-Cell 21Lymphoma, T-Cell 17Leukemia, Biphenotypic, Acute 17Dendritic Cell Sarcoma, Interdigitating 17Immunoblastic Lymphadenopathy 16Neoplasms 14Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 11HIV Infections 10Waldenstrom Macroglobulinemia 7Enteropathy-Associated T-Cell Lymphoma 7Blast Crisis 7Multiple Myeloma 6Lymphoma, T-Cell, Cutaneous 6Lymphoma, AIDS-Related 6

Interventions

Vincristine 4Radiotherapy 3Procarbazine 3Methotrexate 3Cytarabine 3Rituximab 2Prednisolone 2Cyclophosphamide 2motexafin gadolinium 1glutamic acid diethyl ester 1glucarpidase 1fludarabine phosphate 1fludarabine 1axicabtagene ciloleucel 1Simvastatin 1Neuropsychological Tests 1Methylprednisolone 1Magnetic Resonance Spectroscopy 1Leucovorin 1Interleukin 1 Receptor Antagonist Protein 1Glutamine 1Glutamic Acid 1Etoposide 1Doxorubicin 1Dietary Supplements 1Dexamethasone 1Contrast Media 1Bendamustine Hydrochloride 1Baclofen 1AP 1903 reagent 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Neurotoxicity Syndromes × Vincristine × Lymphoid × Clear all
NCT01399372 2023-07-20

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Radiation Therapy Oncology Group

Phase 2 Completed
91 enrolled 17 charts
Lymphoid

Lymphoma, Radiation Injuries, Neurotoxicity Syndromes

NCT00666484 2014-12-04

Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma

University College, London

Phase 2 Completed
47 enrolled
Lymphoid

Hodgkin Disease, Lymphoma, Neurotoxicity Syndromes

NCT00734773 2012-05-18

Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL

Northwestern University

Phase EARLY_PHASE1 Withdrawn
CNSLymphoid

Lymphoma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT00001689 2008-03-04

A Pharmacokinetic and Pharmacodynamic Study of Vincristine in Children With Leukemia

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
90 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Neurotoxicity Syndromes, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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