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Phase

Phase EARLY_PHASE1 1Phase 1 1

Status

Completed 10Active not recruiting 2Withdrawn 1Suspended 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 2Other hematologic neoplasm 1Gastrointestinal 1CNS 1

Conditions

Lymphoma 156Lymphoma, Non-Hodgkin 141Leukemia, Lymphocytic, Chronic, B-Cell 136Precursor Cell Lymphoblastic Leukemia-Lymphoma 132Lymphoma, Follicular 112Lymphoma, Large B-Cell, Diffuse 111Lymphoma, Mantle-Cell 75Lymphoma, B-Cell 73Hodgkin Disease 63Multiple Myeloma 59Leukemia 55Burkitt Lymphoma 51Recurrence 49Lymphoma, B-Cell, Marginal Zone 48Leukemia, Myeloid, Acute 47Neoplasms 45Myelodysplastic Syndromes 42Hematologic Neoplasms 34Waldenstrom Macroglobulinemia 28Leukemia, Myelogenous, Chronic, BCR-ABL Positive 18Lymphoma, T-Cell 17Leukemia, Biphenotypic, Acute 16Leukemia, B-Cell 16Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 15Mycosis Fungoides 15Lymphoproliferative Disorders 15Lymphoma, T-Cell, Peripheral 15Myeloproliferative Disorders 14Lymphoma, T-Cell, Cutaneous 14Breast Neoplasms 14

Interventions

fludarabine phosphate 1fludarabine 1Simvastatin 1Dexamethasone 1Cyclophosphamide 1Bendamustine Hydrochloride 1AP 1903 reagent 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Active not recruiting × Neurotoxicity Syndromes × Lymphoid × Clear all
NCT04514029 2026-01-08

Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel

Masonic Cancer Center, University of Minnesota

Phase EARLY_PHASE1 Active not recruiting
37 enrolled
Lymphoid

Lymphoma, Neurotoxicity Syndromes

NCT03696784 2025-12-08

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

UNC Lineberger Comprehensive Cancer Center

Phase 1 Active not recruiting
19 enrolled
Lymphoid

Cytokine Release Syndrome, Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, B-Cell, Neurotoxicity Syndromes

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